摘要
目的：与常规T1WI、T2WI、T2*WI序列对比，评价磁敏感加权序列（SWI）显示肝硬化门静脉高压患者脾脏Gamna-Gandy小体（Gamna-Gandy body，GGB）的能力。材料与方法：2010年10月—2011年9月对135例肝硬化门静脉高压患者进行磁共振T1WI、T2WI、T2*WI和SWI序列扫描，两名高年资放射科医师在SPIN图像处理软件上分别计算4种序列上GGB阳性患者数量、GGB总数以及直径≤3 mm以及＞3 mm的GGB数量。结果：T1WI、T2WI、T2*WI和SWI序列上GGB阳性患者分别是17、15、38和51例，平均GGB数量分别是（11.1±9.9）、（5.4±5.5）、（28.3±25.5）和（40.9±28.4）个。SWI序列对GGB阳性患者的检出率明显高于T1WI、T2WI、T2*WI序列。SWI序列显示的GGB数量明显多于T1、T2、T2*加权序列，SWI序列在显示直径≤3 mm的GGB上更加优于常规磁共振序列。结论：SWI序列可以更加准确的显示肝硬化门静脉高压患者脾脏GGB数量，是目前检查脾脏GGB最敏感的方法，是常规磁共振扫描的有益补充。
Abstract
Objective: To evaluate the role of abdominal susceptibility weighted imaging(SWI) in the detection of Gamna-Gandy bodies(GGBs) in the spleens of patients with portal hypertension. Materials and Methods: T1WI, T2WI, T2*WI and SWI were performed in 135 patients with portal hypertension. Two radiologists analyzed all the MRI data. The number of patients with GGB in the spleen were determined in four MRI sequences, and the numbers of GGBs were counted in GGB-positive patients. Results: Of the 135 patients with portal hypertension, 51 were GGB positive on SWI, and 17, 15, and 38 were positive on T1WI, T2WI and T2*WI, respectiely. Mean GGB numbers on T1WI, T2WI, T2*WI and SWI were 11.1±9.9, 5.4±5.5, 28.3±25.5, and 40.9±28.4, respectively. The GGB detection rate was significantly greater by SWI than by T1WI, T2WI and T2*WI(χ2=35.69, P<0.05). The number of GGBs detected was significantly greater by SWI than by T1WI, T2WI and T2*WI(P<0.05). Conclusion: SWI is the most sensitive method for detecting GGBs in spleen in patients with portal hypertension.
关键词
高血压 /
门静脉 /
脾疾病 /
磁共振成像
Key words
Hypertension /
portal /
Splenic diseases /
Magnetic resonance imaging
陶 冉;崔进国;周祥峻;田福存;丛 薇;张久权;王 健.
磁共振SWI与常规T1WI、T2WI、T2*WI在门脉高压患者脾脏Gamna-Gandy小体显示中的对比研究[J]. 中国临床医学影像杂志. 2013, 24(07): 489-492
TAO Ran;CUI Jin-guo;ZHOU Xiang-jun;TIAN Fu-cun;CONG Wei;ZHANG Jiu-quan;WANG Jian.
Detection of Gamna-Gandy bodies in the spleen with SWI: compared with T1WI, T2WI, T2*WI[J]. Journal of China Clinic Medical Imaging. 2013, 24(07): 489-492
中图分类号：
Ｒ575.21
Ｒ657.6
Ｒ445.2
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