摘要
目的：探讨18F-FDG PET/CT全身显像在原发性小肠肿瘤中的诊断价值。方法：总结38例小肠病变患者18F-FDG PET/CT的显像资料，均经手术或活检（37例）以及3年内随访（1例）证实，将18F-FDG PET/CT诊断结果与病理结果进行对照分析，评估18F-FDG PET/CT的诊断价值。结果：38例患者，FDG高摄取病变33例（另外2例SUVmax分别为1.6、2.3，在小肠生理性低摄取的背景下亦能准确发现病灶），其中肿瘤性病变占87.9%（29/33），良恶性病变代谢SUVmax值无统计学意义。CT以小肠新生物为肿瘤性病变最主要征象，包括肠管的局限性增厚（17/31）和软组织肿块（20/31）。3例假阳性（均有明确高代谢病灶，均发生肠梗阻）和1例假阴性（新生物及高代谢均不明显），18F-FDG PET/CT全身显像诊断原发性小肠病变的敏感度96.8%（30/31），特异度57.1%（4/7），假阳性率42.9%，假阴性率3.2%，准确度89.5%（34/38）。结论：18F-FDG PET/CT对原发性小肠肿瘤具有很高的诊断效能，但对于部分代谢较高的良性病变和代谢较低的恶性肿瘤易误诊，需引起相关诊断工作人员的重视。
Abstract
Objective: To investigate the diagnostic value of PET/CT with fluorine-18-labeled fluorodeoxyglucose(FDG) for primary small intestine tumors. Method: 18F-FDG PET/CT imaging findings were retrospectively analyzed in 38 cases with the small intestine diseases, of which 37 cases were proved by pathology after operation or biopsy and one case was confirmed after a 3-year follow-up. The images were interpreted and compared with the histopathologic findings to assess the value of 18F-FDG PET/CT in detecting primary small intestinal malignant tumors. Results: Among 38 patients, 33 cases had high FDG uptake, 87.9%（29/33） of which were small intestinal malignant tumors. There was no statistical significance in SUVmax value between malignant neoplasms and benign lesions. The main manifestations of small intestinal tumors were focal thickening of intestines and soft tissue masses on CT images. Three cases were false positive and one case was false negative. The sensitivity, specificity, diagnostic accuracy, false positive rate and false negative rate of 18F-FDG PET/CT were 96.8%, 57.1%, 89.5%, 42.9% and 3.2%, respectively. Conclusion: 18F-FDG PET/CT was of great value for the diagnosis of primary small intestinal tumors.However, the benign lesions with high uptake and the malignant lesions with low uptake were easy to be misdiagnosed, demanding more attention for diagnosis.
关键词
肠肿瘤 /
氟脱氧葡萄糖F18 /
正电子发射断层显像术
Key words
Intestinal neoplasms /
Fluorodeoxy glucose F18 /
Positron-emission tomography
陶超超;王燕华;赵春雷;许尚文;席继辉;陈自谦.
18F-FDG PET/CT显像在原发性小肠肿瘤中的诊断价值[J]. 中国临床医学影像杂志. 2014, 25(11): 787-792
TAO Chao-chao;WANG Yan-hua;ZHAO Chun-lei;XU Shang-wen;XI Ji-hui;CHEN Zi-qian.
Diagnostic value of 18F-FDG PET/CT imaging in primary small intestine tumors[J]. Journal of China Clinic Medical Imaging. 2014, 25(11): 787-792
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