摘要
目的：探讨弥散加权成像（DWI）与磁共振动态增强（DCE-MRI）在前列腺癌分期诊断中的应用价值。材料与方法：回顾性分析48例经病理证实为前列腺癌的患者的DWI及DCE-MRI影像学资料，并与病理结果和临床分期对照。结果：48例前列腺癌中DWI结合DCE-MRI诊断≤B期11例、C期23例、D期14例，分期准确性为85.4%，≤B期、C期、D期的表观扩散系数（ADC）值分别为（0.85±0.15）×10-3 mm2/s、（0.73±0.13）×10-3 mm2/s和（0.64±0.09）×10-3 mm2/s，经统计学分析，三期差异有统计学意义（F=8.06，P<0.05）。Spearman相关分析表明癌区ADC值与肿瘤分期呈负相关（r=-0.53，P<0.01）。结论：DWI结合DCE-MRI对前列腺癌分期的准确性较高，可以用于前列腺癌的分期。
Abstract
Objective: To explore the diagnostic value of diffusion weighted imaging(DWI) and magnetic resonance dynamic contrast-enhanced imaging(DCE-MRI) in the staging of prostate cancer. Materials and Methods: DWI and DCE-MRI data of 48 cases of pathologically proved prostate cancer was retrospectively analyzed, and correlated with pathology and tumor staging． Results: Of the 48 cases, DWI and DCE-MRI diagnosed 11 cases of stage ≤B, 23 cases of stage C and 14 cases of stage D. The accuracy of tumor staging was 85.4%. The mean apparent diffusion coefficient(ADC) values of the tumor regions were (0.85±0.15)×10-3 mm2/s, (0.73±0.13)×10-3 mm2/s and (0.64±0.09)×10-3 mm2/s, respectively. There was statistical significance among the three stages(F=8.06, P<0.05). Spearman correlation analysis showed the ADC values in cancerous regions were negatively correlated with tumor staging(r=-0.53, P<0.01). Conclusions: The accuracy of ADC and DCE-MRI is high in staging of prostate cancer, and ADC combined with DCE-MRI might be useful to the staging of prostate cancer.
关键词
前列腺肿瘤 /
磁共振成像
Key words
Prostatic neoplasms /
Magnetic resonance imaging
孙 静;敖炜群;耿 和;吴 瑜;史维雅;俞晶晶.
DWI结合DCE-MRI在前列腺癌分期诊断中的应用[J]. 中国临床医学影像杂志. 2014, 25(12): 870-873
SUN Jing;AO Wei-qun;GENG He;WU Yu;SHI Wei-ya;YU Jing-jing.
The diagnostic value of DWI combined with DCE-MRI in staging of prostate cancer[J]. Journal of China Clinic Medical Imaging. 2014, 25(12): 870-873
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