摘要
目的：探讨18F-FDG PET/CT对乳腺癌术后复发及转移诊断中的临床价值。方法：收集2008年1月—2012年12月临床怀疑乳腺癌术后复发及转移的女性患者58例，年龄32~79岁，平均52.7岁，所有患者乳腺原发病灶均由手术病理确诊，其中乳腺导管原位癌2例，乳腺浸润性小叶癌1例，髓样癌1例，叶状肿瘤1例，余均为浸润性导管癌。患者均进行18F-FDG PET/CT全身显像，应用半定量分析法和目测法判断结果。结果：58例患者中，7例复发，34例转移，局部复发病灶的SUVmax从3.64到18.70，平均SUVmax为8.04。18F-FDG PET/CT诊断乳腺癌术后复发及转移的灵敏度为97.50%，特异度为88.89%，诊断准确度为94.83%，阳性预测值为95.12%，阴性预测值为94.12%。结论：18F-FDG PET/CT显像能准确诊断乳腺癌复发及转移，能为指导临床制定正确的治疗方案提供重要信息，是监测乳腺癌术后复发及转移的一种有效方法。
Abstract
Objective: To investigate the clinical value of 18F-FDG PET/CT in the diagnosis of recurrence and metastasis in post-operative breast cancer. Methods: From January 2008 to December 2012, whole body 18F-FDG PET/CT imaging with attenuation correction was performed in 58 female patients with suspected recurrent or metastasis of breast cancer, age ranged from 32yrs old~79yrs old with an average of 52.7 years old． The primary breast lesions were all confirmed by surgery and pathology. Among these cases, 2 were ductal carcinoma in situ, 1 case was breast invasive lobular carcinoma, 1 was medullary carcinoma, 1 was phyllodes tumor, the rest were invasive ductal carcinoma. Results: Among the 58 cases, 7 cases were recurrence, 34 cases were of metastasis. The range of SUVmax of the local recurrent lesions was 3.64~18.70, with an average of 8.04. The sensitivity, specificity, accuracy, positive predictive value and negative predictive value of 18F-FDG PET/CT in the diagnosis of breast cancer recurrence and metastasis were 97.50％, 88.89％, 94.83％, 95.12％ and 94.12%, respectively. Conclusion: 18F-FDG PET/CT imaging can accurately diagnose breast cancer recurrence and metastasis, can provide important information for clinical establishment of a right treatment plan, and is valuable in monitoring of breast cancer recurrence and metastasis.
关键词
乳腺肿瘤 /
肿瘤转移 /
正电子发射断层显像术 /
体层摄影术 /
X线计算机
Key words
Breast neoplasms /
Neoplasm metastasis /
Positron-emission tomography /
Tomography /
X-ray computed
戴文静;张 伟;姚立辉;韩 露;王慧颖;辛 军.
18F-FDG PET/CT对乳腺癌术后复发及转移的诊断价值[J]. 中国临床医学影像杂志. 2014, 25(4): 233-236
DAI Wen-jing;ZHANG Wei;YAO Li-hui;HAN Lu;WANG Hui-ying;XIN Jun.
Diagnostic value of 18F-FDG PET/CT in recurrent and metastatic breast cancer[J]. Journal of China Clinic Medical Imaging. 2014, 25(4): 233-236
中图分类号：
Ｒ737.9
R814.42
Ｒ817.4
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