摘要
目的：探讨使用GE signa 1.5T MR机扫描正常学龄前儿童腹部实质性脏器表观扩散系数 (ADC值)均值范围。方法：60例健康学龄前儿童行腹部DWI检查，最大b值分别使用500 s/mm2、700 s/mm2、1 000 s/mm2。在ADC图上测量肝脏、脾脏、肾脏、胰腺的ADC值并进行比较，三组比较用随机区组方差分析，每两组间ADC值比较用LSD法，P<0.05差异具有统计学意义。结果：正常学龄前儿童肝脏、脾脏、肾脏、胰腺在b值分别为500 s/mm2、700 s/mm2、1 000 s/mm2时的ADC值（×10-3 mm2/s，x±s）分别为1.37±0.05、0.78±0.06、1.75±0.07、1.60±0.05；1.20±0.06、0.64±0.05、1.61±0.05、1.47±0.07；1.11±0.08、0.59±0.07、1.49±0.06、1.38±0.08。不同b值时同一脏器 ADC值有统计学差异；同一b值时4种实质性脏器ADC值有统计学差异。结论：正常学龄前儿童腹部实质性脏器的ADC值差异有显著性，按照ADC值由大到小排序为：肾脏、胰腺、肝脏、脾脏。为今后应用DWI诊断腹部实质性脏器疾病提供一定的正常值参考数据。
Abstract
Objective: To investigate the normal apparent diffusion coefficient(ADC) values of the abdominal organs of the preschool healthy children on a 1.5T MR. Methods: Sixty healthy preschool children were examined with DWI using b values including 500 s/mm2, 700 s/mm2 and 1 000 s/mm2. The ADCs were calculated with ROIs positioned in the parenchyma of the liver, kidney, spleen and pancreas. The ADCs were compared statistically using analysis of variance(ANOVA), P<0.05, was considered as significant. Results: There was a statistically significant difference in ADC values among the same parenchyma organs at different b values. There was a statistically significant difference in ADC values among the four solid organs at same b values. Conclusions: The ADCs of parenchyma organs in the abdomen of preschool healthy children were kidney>pancreas>liver>spleen. This study provide valuable refence for the diagnosis of parenchyma organ disease by using DWI.
关键词
腹部 /
儿童 /
学龄前 /
磁共振成像
Key words
Abdomen /
Child /
preschool /
Magnetic resonance imaging
林飞飞;干芸根;孙龙伟;叶文宏;曾伟彬.
学龄前儿童正常腹部实质脏器MRI扩散加权成像ADC值研究[J]. 中国临床医学影像杂志. 2014, 25(6): 413-416
LIN Fei-fei;GAN Yun-gen;SUN Long-wei;YE Wen-hong;ZENG Wei-bin.
Investigation of apparent diffusion coefficient of solid abdominal organs in preschool healthy children[J]. Journal of China Clinic Medical Imaging. 2014, 25(6): 413-416
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