摘要
目的：本研究运用临床无创的彩色多普勒血流显像作为研究手段，探讨肾血流在儿童和成人体外循环（CPB）术后改变特点。方法：对12例儿童和12例成人心脏病患者，在实施CPB心脏直视手术前，术后1 h、2 h、4 h、8 h、16 h、24 h，运用彩色多普勒血流显像分别监测各时点肾主动脉、肾段动脉阻力指数（RI），并同时检测肾功能尿素氮（Urea）、尿酸（UA）、肌酐（Crea），对所有数据进行统计分析。结果：儿童组患者肾功能各指标在术后8 h、16 h、24 h较术前明显增高，在16 h后肾功能逐渐趋于好转；成人肾功能在术后也呈现增高趋势，但通过统计分析差异不具有统计学意义。通过检测两组患者术后RI值均存在改变，术后1 h检测肾血流RI即发生明显增高，后逐渐恢复；儿童组较成人组RI改变更为明显。结论：体外循环术后1 h肾血流RI即明显增高，对于儿童肾脏功能和肾血流RI改变较成人更明显。
Abstract
Objective: To explore the changing characteristics of the renal blood flow resistance index(RI) after cardiopulmonary bypass(CPB) in both children and adults by noninvasive color Doppler flow imaging(CDFI). Methods: All patients with heart disease were divided into two groups according to age, children’s group(n=12) and adult group(n=12). The RI of main renal artery and renal segmental artery in all cases were monitored by the CDFI at the preoperative and postoperative 1 h, 2 h, 4 h, 8 h, 16 h, 24 h. The renal blood urea nitrogen(Urea), uric acid(UA) and creatinine(Crea) were detected at the same time. All data for statistical analysis. Results: In children’s groups, various indicators of renal function at postoperative 8 h, 16 h, 24 h were significantly higher than those at preoperation, the renal function gradually got better after 16 h postoperation. Adult kidney function also showed an increasing trend at postoperative time, but the statistical data had no significant differences. RI values were changed at postoperative time in both groups. RI values at 1 h postoperation was significantly higher than that of other times, then gradually recovered. RI values changed more apparently in children’s groups. Conclusion: RI values at 1 h postoperation was significantly higher than other times. Renal function and renal blood flow RI changed more evident in children than in adults.
关键词
肾功能试验 /
体外循环 /
超声检查 /
多普勒 /
彩色
Key words
Kidney function tests /
Extracorporeal circulation /
Ultrasonography /
Doppler /
color
刘 慧;付 勇;陈晓梅;邓明彬;于风旭;李明星.
肾血流阻力指数在儿童和成人体外循环术后改变特点研究[J]. 中国临床医学影像杂志. 2014, 25(6): 422-425
LIU Hui;FU Yong;CHEN Xiao-mei;DENG Ming-bin;YU Feng-xu;LI Ming-xing.
Study of characteristics of renal blood flow resistance index change after cardiopulmonary bypass in children and adults[J]. Journal of China Clinic Medical Imaging. 2014, 25(6): 422-425
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