胼胝体压部可复性局灶孤立性病变的MRI诊断价值

郑奎宏; 马林; 王亚明; 黄敏华; 王子军; 邵立新; 应立刚

中国临床医学影像杂志 ›› 2014, Vol. 25 ›› Issue (7) : 457-459.

论著

胼胝体压部可复性局灶孤立性病变的MRI诊断价值

郑奎宏1，马林2，王亚明1，黄敏华1，王子军1，邵立新1，应立刚1

作者信息 +

Neuroimaging diagnostic value of intraaxial reversible focal isolated lesions in the splenium of the corpus callosum

ZHENG Kui-hong1, MA Lin2, WANG Ya-ming1, HUANG Min-hua1, WANG Zi-jun1, SHAO Li-xin1, YING Li-gang1

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文章历史 +

摘要

目的：脑内胼胝体压部出现可复性局灶孤立性病变是一种少见的MRI表现，本研究的目的在于描述该病变的MRI特点并分析该病变的影像诊断价值。方法：回顾性分析3例MRI表现为胼胝体压部局灶孤立性病变患者的影像及临床资料，并复习相关文献。结果：1例流感患者出现精神症状，MRI检查提示胼胝体压部出现孤立局灶性异常信号，临床确诊流感病毒相关性脑炎，经抗病毒治疗后患者完全康复，复查MRI病灶完全消失；1例癫痫患者服用抗癫痫药物多年，术前行MRI检查偶然发现胼胝体压部局灶孤立性异常信号，术后复查病灶明显缩小；1例精神异常患者行MRI检查发现脑内胼胝体压部出现局灶孤立性异常信号，随后的脊髓MRI检查发现髓内弥漫性异常信号，临床诊断急性播散性脑脊髓炎，1月后患者完全康复，复查MRI病变已完全消失。结论：胼胝体压部局灶孤立性异常信号无法用某一种疾病解释，多种疾病脑内均可以见到此类异常信号，MRI胼胝体压部局灶性异常信号是一种非特异性表现。

Abstract

Objective: A focal isolated lesion in the splenium of the corpus callosum(SCC) is a rare finding in MRI. The aim of the present study was to describe MR imaging findings of the SCC lesion and to analyze the relationship between this lesion and possible etiologic factors. Methods: Three patients with SCC lesion on MRI were reviewed. The imaging findings on MRI were analyzed. The clinical records and literature were also reviewed. Results: The first patient with influenza presented with mental symptom showed a lesion in the central portion of the splenium. After receiving antiviral medication, his neurological deficits completely recovered, and the diagnosis of virus-associated encephalitis was made. Two weeks later, the lesion completely disappeared. The second patient with epilepsy presented with signal abnormalities in the SCC in the context of presurgical epilepsy, the patient had received antiepileptic drugs for years. One week after operation for epilepsy, MR examination showed a clear reduction in lesion size. The last patient presented with abnormal neurological findings, and MRI showed an isolated SCC lesion and diffuse abnormal intensity in spinal cord. The diagnosis of acute disseminated encephalomyelitis(ADEM) was made and the recovery was complete in one month. Follow-up MR examinations showed complete disappearance of the SCC lesion. Conclusion: There is not a single condition or disease responsible for SCC lesion. These lesions are detected in a relatively large number of conditions with heterogeneous etiopathogenetic factors and a focal SCC lesion on MRI is a nonspecific finding.

导出引用

郑奎宏;马林;王亚明;黄敏华;王子军;邵立新;应立刚. 胼胝体压部可复性局灶孤立性病变的MRI诊断价值[J]. 中国临床医学影像杂志. 2014, 25(7): 457-459

ZHENG Kui-hong;MA Lin;WANG Ya-ming;HUANG Min-hua;WANG Zi-jun;SHAO Li-xin;YING Li-gang. Neuroimaging diagnostic value of intraaxial reversible focal isolated lesions in the splenium of the corpus callosum[J]. Journal of China Clinic Medical Imaging. 2014, 25(7): 457-459

中图分类号： Ｒ512.3 Ｒ445.2