不同b值时正常前列腺ADC值变化与年龄相关性研究

张方璟; 朱记超; 陈燕萍

中国临床医学影像杂志 ›› 2015, Vol. 26 ›› Issue (1) : 34-37.

论著

不同b值时正常前列腺ADC值变化与年龄相关性研究

张方璟1，朱记超2，陈燕萍3

作者信息 +

The study of relationship between ADC values and ages in different regions of normal prostate at different b values

ZHANG Fang-jing1, ZHU Ji-chao2, CHEN Yan-ping3

Author information +

文章历史 +

摘要

目的：通过对正常前列腺行并行采集弥散加权成像，比较不同b值时，正常前列腺各区带表观弥散系数（ADC）值的变化情况以及随着年龄的增加前列腺各区带ADC值的变化。方法：回顾性分析正常前列腺DWI检查者29例，分为2组：正常中青年组（21~50岁）14例，无症状老年组（51~79岁）15例，b值选用300、600、800、1 000 s/mm2。结果：相同b值，正常前列腺外周带DWI信号与ADC值高于中央腺，外周带与中央腺ADC值比较差异有显著性（P<0.05）；相同b值，老年组前列腺外周带及中央腺DWI信号与ADC值高于中青年组，相同区带ADC值比较差异有显著性（P<0.05）；不同b值，同一年龄组相同区带ADC值间存在显著性差异（P<0.05），b值越高，ADC值越小；年龄与前列腺外周带及中央腺的ADC值呈显著的正相关（P<0.05）。结论：相同b值下，正常前列腺外周带的ADC值高于中央腺，b值越大，ADC值越小；随着年龄的增长，前列腺外周带及中央腺的ADC值增加，因此运用ADC值诊断前列腺疾病时，要考虑年龄的因素。

Abstract

Objective: To analyze and compare the changes of apparent diffusion coefficient(ADC) values of peripheral zone(PZ) and central gland(CG) in normal prostate gland and that of different age groups by 3.0T diffusion-weighted MR imaging(DWI) with array spatial sensitivity encoding(ASSET) technique at different b values. Methods: 29 patients who underwent prostate DWI scanning were enrolled in this study. These patients were divided into two groups as followed: young adult normal group(age from 21 to 50 years old), 14 cases; symptomless aged group(age from 51 to 79 years old), 15 cases. b values were 300, 600, 800 and 1 000 s/mm2. Results: The signal intensity of DWI and ADC values in the PZ were both higher than that in CG at the same b values in two groups. Statistically significant difference(P<0.05) was found in ADC values between PZ and CG. The signal intensity of DWI and ADC values of PZ and CG in the aged group were higher than that in the youth adult group at the same b value. Statistically significant difference(P<0.05) was found in ADC values at the same region. Statistically significant difference(P<0.05) was found in ADC values among four different b values at the same region. The lower the ADC values were, the larger the b values were. Positive correlations existed between age and the ADC values of PZ and CG significantly. Conclusion: The ADC values of PZ are higher than that in CG in normal prostate at the same b value. The higher the b values are, the lower the ADC values are. The ADC values of PZ in prostate increased as age increased. Age should be considered when prostatic diseases were diagnosed with ADC values.

导出引用

张方璟;朱记超;陈燕萍. 不同b值时正常前列腺ADC值变化与年龄相关性研究[J]. 中国临床医学影像杂志. 2015, 26(1): 34-37

ZHANG Fang-jing;ZHU Ji-chao;CHEN Yan-ping. The study of relationship between ADC values and ages in different regions of normal prostate at different b values[J]. Journal of China Clinic Medical Imaging. 2015, 26(1): 34-37

中图分类号： Ｒ697.3 Ｒ445.2