目的：探讨脑皮质层状坏死（CLN）的MRI影像特点，提高对本病的认识。方法：回顾性分析2012年1月—2014年10月我院神经内科诊治的17例CLN患者的MRI影像资料，总结其MRI影像特点。结果：17例中双侧大脑半球病变3例，单侧大脑半球病变14例。1个脑叶受累11例，2个脑叶受累4例，多个脑叶受累2例。CLN检出时间为12～32 d。病变于MRI T1WI及FLAIR上均表现为脑回状高信号，MRA原始图像上显示更清晰；DWI上12例呈高信号，但信号较T1WI上弱，T2WI上病变显示不清，6例辅助SWAN检查均未发现与皮层高信号范围相符的出血灶。结论：CLN具有典型的MRI影像特征，即T1WI呈脑回状高信号，结合临床病史不难诊断。
Abstract
Objective: To investigate the MR imaging features of cerebral cortical laminar necrosis(CLN). Methods: The MR imaging materials of 17 CLN patients diagnosed in our hospital ranged from January 2012 to October 2014 were retrospectively analyzed. The MRI characteristics were studied. Results: CLN was detected from 12 to 32 d since the patients were admitted. The affected regions were bilateral cerebral hemisphere(3/17), unilateral cerebral hemisphere(14/17), then the single lobe(11/17), double lobes(4/17), multiple lobes(2/17). On MRI, the gyral shape lesion showed high intensity on T1WI and fluid-attenuated inversion-recovery(FLAIR), lesions showed more clearly on original three dimensional time of flight magnetic resonance angiography(3D-TOF MRA) images, ill defined on T2WI, 12 patients manifested as high intensity on DWI. No hemorrhagic focus showed on SWAN in 6 patients. Conclusion: Typical imaging features could be revealed in CLN, which is high intensity on MRI T1WI. Accurate diagnosis could be obtained with imaging examination in combination with clinical history.
关键词
脑疾病 /
磁共振成像
Key words
Brain diseases /
Magnetic resonance imaging
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参考文献
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