目的：探讨磁共振三维时间飞跃法扰相梯度回波序列（Three-dimensional time of flight fast low angle shot sequence，3D-TOF FLASH）与容积内插屏气检查（Volumetric interpolated breath-hold examination，VIBE）在三叉神经痛诊断方面的临床价值。方法：对47例经临床诊断为三叉神经痛的患者分别进行大体素及小体素模式下的3D-TOF FLASH与VIBE序列检查，比较两种扫描序列下三叉神经的信噪比（Signal-to-noise ratio，SNR）、载噪比（Carrier noise ratio，CNR）及周围血管显现数目，评价两种序列在三叉神经痛中的诊断价值。结果：VIBE序列图像的三叉神经SNR、CNR值均较3D-TOF FLASH序列图像显著升高，差异具有统计学意义（P<0.05），并且三叉神经周围血管显示的数目明显增多（P<0.05）。大体素扫描模式下，应用两种序列进行扫描，相较小体素模式，三叉神经的SNR、CNR值均升高且周围血管显示数目均增多（P<0.05）。结论：在进行磁共振断层血管成像（MRTA）扫描时，应用大体素3D-TOF FALSH序列对三叉神经进行扫描，能够快速、准确地分辨责任动脉血管；而使用VIBE序列进行扫描，能够对脑桥小脑角池内的三叉神经及其周围血管进行更为精确的显示。
Abstract
Objective: To evaluate the clinical value of MR three-dimensional time of flight fast low angle shot sequence(3D-TOF FLASH) and volumetric interpolated breath-hold examination(VIBE) sequence in diagnosis of trigeminal neuralgia. Method: Forty-seven patients with trigeminal neuralgia underwent 3D-TOF FLASH and VIBE of large and small voxel mode respectively. The signal-to-noise ratio(SNR), carrier noise ratio(CNR) and the number of peripheral vessels of two scanning sequences were compared, the diagnostic values of two sequences were evaluated in trigeminal neuralgia. Results: The CNR and SNR values of trigeminal nerve of VIBE sequence were significantly higher than those of 3D-TOF FLASH sequence, the difference was statistically significant(P<0.05), and the number of peripheral vessels of the trigeminal nerve was significantly increased(P<0.05). Compared with the small voxel mode, the CNR, SNR values and the number of peripheral vessels of trigeminal nerve of the large voxel mode in two scanning sequences were increased(P<0.05). Conclusion: The application of 3D-TOF FLASH sequence of the large voxel mode in trigeminal nerve can quickly and accurately distinguish responsible arteries; and the application of VIBE sequence can display the trigeminal nerve in the cerebellopontine angle pool and peripheral vessels more precisely in magnetic resonance tomographic angiography(MRTA).
关键词
三叉神经痛 /
磁共振成像
Key words
Trigeminal neuralgia /
Magnetic resonance imaging
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