摘要
目的：探讨分子影像SPECT/CT对乳腺癌骨转移的临床应用价值。方法：回顾性分析多层螺旋CT与SPECT/CT融合显像对68个疑似乳腺癌骨转移病灶的检查结果，进行统计学检验。结果：经临床确诊乳腺癌骨转移的55个病灶中：MSCT诊断的敏感度为78.2％（43/55），特异性为92.3%（12/13），准确性为80.9%（55/68）；SPECT/CT融合显像诊断敏感度为96.4％（53/55），特异性为76.9%（10/13），准确性为92.6%（63/68）。2种检查方法的敏感度、准确性差异有统计学意义（P＜0.05），特异性差异无统计意义。结论：SPECT/CT融合显像相对于MSCT检查，可提高对乳腺癌骨转移的诊断敏感性和准确性，具有较好的临床应用价值。
Abstract
Objective: To investigate the clinical application value of the molecular imaging SPECT/CT for bone metastases of breast cancer. Methods: Both MSCT and SPECT/CT imaging data of 68 suspicious bone metastases lesions of breast cancer were retrospectively analyzed and compared, and the statistics checkout was carried out. Resluts: Among the 55 bone metastases lesions of breast cancer, sensitivity, specificity and accuracy of bone metastases diagnosed by MSCT were 78.2％(43/55), 92.3%(12/13) and 80.9%(55/68); and sensitivity, specificity and accuracy of bone metastases diagnosed by SPECT/CT were 96.4％(53/55), 76.9%(10/13) and 92.6%(63/68). For the difference of the sensitivity and accuracy, there was statistically significance between MSCT and SPECT methods(P＜0.05), and the specificity of both methods was no difference. Conclusions: Comparing with MSCT, the SPECT/CT fusion imaging can improve the sensitivity and accuracy of the bone metastases diagnosis of breast cancer, and having better clinical application value.
关键词
乳腺肿瘤 /
肿瘤转移 /
体层摄影术 /
发射型计算机 /
单光子
Key words
Breast neoplasms /
Neoplasm metastasis /
Tomography /
emission-computed /
single-photon
董 科;傅健飞;楼菁菁;刘 江.
分子影像SPECT/CT对乳腺癌骨转移的临床应用价值[J]. 中国临床医学影像杂志. 2015, 26(7): 465-468
DONG Ke;FU Jian-fei;LOU Jing-jing;LIU Jiang.
The clinical application value of molecular imaging SPECT/CT for bone metastases from breast cancer[J]. Journal of China Clinic Medical Imaging. 2015, 26(7): 465-468
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