摘要
目的：探讨儿童胸膜肺母细胞瘤（PPB）的影像学及临床病理表现，提高对本病的认识。方法：回顾性分析经手术病理及免疫组化证实的12例PPB的影像学资料，根据病理切片、免疫组织化学按Dehner分型分为Ⅰ、Ⅱ、Ⅲ三型；根据不同分型的X线和CT特点，将影像表现与病理进行对照分析。结果：PPB Ｘ线表现为胸腔内巨大占位病变，肺及纵隔结构受压。CT表现：胸膜下肺外围非均匀性巨大软组织肿块，常伴有胸腔积液、肺不张。增强扫描肿瘤实性成分呈不均匀明显强化，囊性成分无强化。镜检：肿瘤主要由原始胚胎性的圆形或卵圆形细胞组成。免疫组化：Vimentin（+），Desmin（+）。结论：PPB影像学表现不典型，确诊需依靠病理及免疫组织化学检验相结合。
Abstract
Objective: To explore the images and clinical pathologic features of pleuropulmonary blastoma(PPB) and to improve the understanding of this disease. Methods: The imaging findings of 12 cases of PPB confirmed by pathology were analyzed retrospectively. They were divided into the Ⅰ, Ⅱ, Ⅲ types according to Dehuer calssfication. According to X-ray and CT examination in PPB of different types, the images and pathological features were analyzed. Results: A large mass of PPB was shown on X-ray image in thoracic cavity, which could oppress lung and mediastinal. A huge heterogeneous density mass beneath the pleura lung periphery was shown on CT image, often associated with pleural effusion, atelectasis. In post-contrasted enhancement image, the solid component showed obvious enhancement, while the cystic component showed no enhancement. Primitive embryonal round or oval cells were mainly composed of the tumor by microscopic examination. Vimentin and Desmin were shown positive in the immunohistochemical study. Conclusion: The diagnosis of PPB should be based on both the pathological and immunohistochemical evidences duing to lacking of photography features.
关键词
肺肿瘤 /
儿童 /
体层摄影术 /
螺旋计算机
Key words
Lung neoplasms /
Child /
Tomography /
spiral computed
胡悦林;刘鸿圣;高 秋;黄 莉;鹿连伟;肖伟强;周 宁.
儿童胸膜肺母细胞瘤的影像学表现及临床病理分析[J]. 中国临床医学影像杂志. 2015, 26(7): 469-472
HU Yue-lin;LIU Hong-sheng;GAO Qiu;HUANG Li;LU Lian-wei;XIAO Wei-qiang;ZHOU Ning.
Imaging features and clinical pathological analysis of pleuropulmonary blastoma in children[J]. Journal of China Clinic Medical Imaging. 2015, 26(7): 469-472
中图分类号：
R743.2
Ｒ743.3
Ｒ814.42
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