摘要
目的：探讨恶性血液病治疗后颅脑并发症的MRI表现。方法：收集30例经骨髓穿刺证实的恶性血液病患者（白血病25例，淋巴瘤4例，多发性骨髓瘤1例），均排除了其对中枢神经系统的侵犯。通过MRI表现研究恶性血液病治疗后中枢神经系统的改变。结果：MRI发现30例患者均有颅脑并发症，其中14例患者有2种或2种以上并发症，包括脑出血2例、脑白质病变21例、脑梗死8例、脑萎缩16例、真菌感染1例。结论：MRI对恶性血液病治疗后相关颅脑并发症的显示较敏感，是最佳影像学检查方法，头颅MRI检查可早期发现病变并指导临床相关治疗。
Abstract
Objective: To study the MRI features of cerebral complications in treatment of malignant hematological diseases. Methods: Thirty cases of malignant hematological diseases without invasion of central nervous system, including 25 cases of leukemia, 4 cases of lymphoma, a case of multiple myeloma, confirmed by bone marrow biopsy were enrolled in the study. We studied the changes of brain MRI after therapy. Results: All of the 30 patients had cerebral complications, and 14 patients had at least 2 complications, including 2 cases of hemorrhage, 21 cases of cerebral white matter lesions, 8 cases of cerebral infarction, 16 cases of cerebral atrophy, a case of fungal infection. Conclusion: MRI is the best imaging method for cerebral complications in chemotherapy and transplantation of malignant hematopoiesis. It’s sensitive and can be used to found the changes earlier to guide the treatment.
关键词
血液肿瘤 /
脑疾病 /
磁共振成像
Key words
Hematologic neoplasms /
Brain diseases /
Magnetic resonance imaging
侯学文;于海涛;祝安惠;张晓锦.
恶性血液病化疗及移植后颅脑并发症的MRI诊断[J]. 中国临床医学影像杂志. 2015, 26(8): 554-557
HOU Xue-wen;YU Hai-tao;ZHU An-hui;ZHANG Xiao-jin.
MRI diagnosis of cerebral complications in chemotherapy and transplantation of malignant hematopoiesis[J]. Journal of China Clinic Medical Imaging. 2015, 26(8): 554-557
中图分类号：
Ｒ733.7
Ｒ742
Ｒ445.2
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