摘要
目的：应用3D MPRAGE双倍Gadobutrol延迟增强扫描技术对与皮层相关脑转移瘤的分型及定义。方法：回顾性分析经本院病理证实脑转移瘤患者25例，所有患者均行常规轴位T1WI、T2WI和FLAIR及3D MPRAGE序列延迟增强扫描。在3D MPRAGE增强扫描图像上对转移瘤进行分型及定义，分三型：Ⅰ型为转移瘤完全位于脑皮层内，瘤体直径小于皮层宽度。Ⅱ型转移瘤边缘紧邻脑皮层边缘。Ⅲ型为转移瘤横跨在脑皮髓交界区，侵入髓质内。结果：应用3D MPRAGE双倍剂量Gadobutrol延迟增强技术发现与皮层相关转移瘤121个，Ⅰ型病灶6个，Ⅱ型病灶10个，Ⅲ型病灶105个，Ⅲ型占总比例的95.7%，转移瘤直径与分型呈正相关rs=0.441，P<0.05。结论：根据3D MPRAGE双倍Gadobutrol延迟增强扫描技术可以显示脑皮层与转移瘤的关系，与皮层有关的转移瘤分为三型。Ⅲ型明显多于Ⅰ和Ⅱ型。
Abstract
Objective: To investigate the classification and definition of intracranial metastasis associating with cerebral cortex by double-dose Gadobutrol and delayed contrast-enhancement of MR scanning using 3D MPRAGE sequences. Methods: Twenty-five patients with suspected intracranial metastases were retrospectively analyzed. All patients underwent MRI examination, which included T1WI, T2WI, FLAIR and delayed contrast-enhancement of MR scanning using 3D MPRAGE sequences.The intracranial metastases were classified and defined according to the images of 3D-MPRAGE. The metastasis, located in the cerebral cortex, at the edge of the cerebral cortex and at the corticomedullary junction, was taken as TypeⅠ, TypeⅡ, Type Ⅲ, respectively. Results: 121 metastatic lesions(6 in typeⅠ, 10 in type Ⅱ, 105 in type Ⅲ) associating with cerebral cortex were found using 3D MPRAGE sequences. Type Ⅲ account for 95.7% of 121 metastatic lesions. There was a positive correlation between the tumor size and tumor typing(rs=0.441, P<0.05). Conclusion: Delayed and double-dose Gadobutrol contrast-enhancement of MR scanning using 3D MPRAGE sequences can clearly display the relationship between intracranial metastasis and cerebral cortex. The intracranial metastasis associating with cerebral cortex were divided into three types and most intracranial metastasis are seen at the corticomedullary junction.
关键词
脑肿瘤 /
肿瘤转移 /
磁共振成像
Key words
Brain neoplasms /
Neoplasm metastasis /
Magnetic resonance imaging
李虹易;段 阳;常灿灿;李延锋;杨本强;刘文源;刘 宇;徐 猛.
与皮层相关脑转移瘤的分型及定义——应用3D MPRAGE双倍Gadobutrol剂量延迟增强扫描技术[J]. 中国临床医学影像杂志. 2015, 26(9): 616-619
LI Hong-yi;DUAN Yang;CHANG Can-can;LI Yan-feng;YANG Ben-qiang;LIU Wen-yuan;LIU Yu;XU Meng.
Classification and definition of intracranial metastasis associating with cerebral cortex: double-dose Gadobutrol and delayed contrast-enhancement 3D MPRAGE[J]. Journal of China Clinic Medical Imaging. 2015, 26(9): 616-619
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