摘要
目的：探讨四维自动左室定量技术（Four dimensional automatic left ventricular quantify，4D Auto LVQ）早期评价系统性红斑狼疮（SLE）患者左室收缩功能的临床应用价值。方法：收集SLE患者28例及正常对照组30例，分别应用4D Auto LVQ技术获得左室舒张末期容积（EDV）、收缩末期容积（ESV）、左室射血分数（LVEF）、心输出量（CO）、球形指数（SPI）、左室舒张末期质量（LV EDmass）及质量指数（LV EDmass Ⅰ）、左室收缩末期质量（LV ESmass）及质量指数（LV ESmass Ⅰ）；左室整体纵向应变（GLS）及局部纵向应变（LS）、整体圆周应变（GCS）及局部圆周应变（CS）、整体面积应变（GAS）及局部面积应变（AS）、整体径向应变（GRS）及局部径向应变（RS），比较两组参数之间的差异。结果：与对照组比较，SLE组虽然LVEF降低、SPI增高，但差异无统计学意义（P＞0.05）。SLE组EDV、ESV、CO、LV EDmass、LV ESmass ＆ LV EDmass Ⅰ、LV ESmass Ⅰ均较对照组明显增高（P＜0.05），两组受试者整体心肌应变（GLS、GCS、GAS、GRS）及大部分节段心肌应变（LS、CS、AS、RS）比较：SLE组均较对照组显著减低（P＜0.05）。结论：4D Auto LVQ技术可早期评价SLE患者左室整体及局部心肌收缩功能受损情况。
Abstract
Objective: To explore the value of four dimensional automatic left ventricular quantify(4D Auto LVQ) to assess left ventricular systolic function early in patients with systemic lupus erythematosus(SLE). Methods: Twenty-eight SLE patients and thirty control subjects underwent the examination of 4D Auto LVQ obtain the segments of left ventricular end-diastolic volume(EDV), left ventricular end-systolic volume(ESV), left ventricular ejection fraction(LVEF), cardiac output(CO), spherical index(SPI), left ventricular end-systolic mass(LV ESmass) and left ventricular end-systolic mass index(LV ESmass Ⅰ), left ventricular end-diastolic mass(LV EDmass) and left ventricular end-diastolic mass index(LV EDmass Ⅰ), global longitudinal strain(GLS) and longitudinal strain(LS), global circumferential strain(GCS) and circumferential strain(CS), global area strain(GAS) and area strain(AS), global radial strain(GRS) and radial strain(RS). Values of these parameters between two groups were compared. Results: Compared with those of the controls, though LVEF lower and SPI higher in SLE groups, but there were no statistically significant difference between the two groups(P＞0.05). EDV, ESV, CO, LV EDmass, LV ESmass and LV EDmass Ⅰ, LV ESmass Ⅰ were significantly higher in SLE group(P＜0.05). GLS, GCS, GAS, GRS and the most of the segments’s strains were decreased in SLE patients compared with controls(P＜0.05). Conclusion: 4D Auto LVQ can be used as early evaluation of left ventricular global and local myocardial systolic function which was damaged in patients with SLE.
关键词
心室功能 /
左 /
收缩 /
红斑狼疮 /
系统性 /
超声心动描记术 /
多普勒 /
彩色
Key words
Ventricular function, left /
Constriction /
Lupus erythematosus, systemic /
Echocardiography, Doppler, color
钱胜利，杨 莉，高菡静，李 延，张 俊，乔 伟.
四维自动左室定量技术评价系统性红斑狼疮患者左室收缩功能的初步研究[J]. 中国临床医学影像杂志. 2016, 27(2): 106-109
QIAN Sheng-li, YANG Li, GAO Han-jing, LI Yan, ZHANG Jun, QIAO Wei.
Evaluation of left ventricular systolic function in patients with systemic lupus erythematosus using#br#
four dimensional automatic left ventricular quantify: a preliminary study[J]. Journal of China Clinic Medical Imaging. 2016, 27(2): 106-109
中图分类号：
Ｒ331.31
Ｒ593.241
Ｒ540.45
{{custom_sec.title}}
{{custom_sec.title}}
{{custom_sec.content}}
参考文献
[1]蒋季杰. 现代红斑狼疮病学[M]. 北京：人民军医出版社，2005：187－199.
[2]Buss SJ, Wolf D, Korosoglou G, et al． Myocardial left ventricular dysfunction in patients with systemic lupus erythematosus: new insights from tissue Doppler and strain imaging[J]． J Rheumatol, 2010, 37(1): 79-86．
[3]李秀云，姜淑英，寇红菊，等. 超声二维半点追踪评价系统性红斑狼疮患者左室收缩功能[J]. 中国临床医学影像杂志，2014，25（1）：29-31.
[4]Zhai H, Mu Y, Guan L, et al. The value of aneurysm volume and myocardial strain rate for evaluating cardiac function of ischemia-related left ventricular aneurysm in a rabbit model using real time three-dimensional echocardiographic imaging combined with speckle tracking imaging[J]. Echocardiography, 2013, 30(7): 837-842.
[5]Nesser HJ, Mor-Avi V, Gorissen W, et al. Quantification of left ventricular volumes using three-dimensional echocardiographic speckle tracking: Comparison with MRI[J]. Eur Heart J, 2009, 30(13): 1565-1573.
[6]段利科，李玲，谢明星，等. 三维斑点追踪技术评价正常人左心室心肌应变的初步研究[J]. 中华医学超声杂志：电子版，2010，7（5）：803-810.
[7]姚鸿梅，李江波，林建兰，等. 面积应变评估正常构型高血压左室收缩功能[J]. 生物医学工程杂志，2013，30（2）：306-311.
[8]Hayat D, Kloeckner M, Nahum J, et al. Comparison of real-time three-dimensional speckle traching to magnetic resonance imaging in patients with coronary heart disease[J]. Am J Cardiol, 2012, 109(2): 180-186.
[9]Kleijn SA, Aly MF, Terwee CB, et al. Three-dimensional speckle tracking echocardiography for automatic assessment of global and regional left ventricular function based on area strain[J]. J Am Soc Echocardiogr, 2011, 24(3): 314-321.
[10]Wen H, Liang Z, Zhao Y, et al. Feasibility of detecting early left ventricular systolic dysfunction using global area strain: A novel index derived from three-dimensional speckle-tracking echocardiography[J]. Eur J Echocardiography, 2011, 12(12): 910-916.
