目的：探讨磁共振FLAIR高信号血管征（HVS）在大脑中动脉供血区脑梗塞患者中的发生特点。方法：回顾性分析急性大脑中动脉供血区脑梗塞患者的影像学资料，按出现症状到行MRI检查时间的不同分为3组，分析总体HVS发生率及各组发生率，比较组间HVS的发生率差异。采用χ2检验分析HVS的发生部位、分布范围及级别与颅底血管狭窄情况及脑梗塞形态的相关性、统计分析不同Willis环类型患者发生HVS的差异。结果：HVS阳性率在≤24 h组为81.82%，2~4 d组为69.35%，5~7 d组为63.41%，HVS总体发生率随时间延长呈下降趋势，然各组间无明显统计学差异。HVS发生随血管狭窄程度增加而增高（P=0.000）。同时，M1段出现HVS时趋向为大片脑梗塞，而M4~5段出现HVS时趋向为散在脑梗塞。Willis环后循环不完整组较完整组出现HVS阳性率显著增高（χ2=7.089，P=0.008）。结论：①HVS在急性大脑中动脉区脑梗塞早期具有较高阳性率，随着时间延长而降低。②脑血管狭窄程度越严重其HVS分布越广泛且级别越高。③M1段出现HVS趋向为大面积脑梗塞，M4~5段HVS趋向为散在小片脑梗塞。④Willis环缺损是脑梗塞形成的一个重要影响因素。Willis环后循环缺损患者HVS发生率显著高于后循环完整者。

Objective: To evaluate the characteristics of high-intense vessel sign(HVS) on FLAIR in patients with cerebral infarction in middle cerebral artery(MCA). Methods: Patients with acute cerebral infarction in MCA were retrospectively analyzed and were divided into three groups according to time which occurred symptoms to MRI examination. The overall and each group incidence of HVS were analyzed and compared. The correlation between location distribution grade of HVS and vascular stenosis, cerebral infarction form were analyzed by Chi-square test. The differences among three groups were compared. Results: The positive rate of HVS was 81.82%(≤24 hours), 69.35%(2~4 days) and 63.41%(5~7 days) respectively. The incidence rate was descending accompanying the time prolonging. There was no significant difference among three groups. While the incidence rate of HVS was ascending accompanying the vascular stenosis degree arising(P=0.000). HVS appeared in M1 segment trended large part of cerebral infarction, and HVS appeared in the M4~5 segment trended for dispersive cerebral infarction. High positive rate of HVS was occurred more in intermitted group than that in integrity group(χ2=7.089, P=0.008). Conclusion: ①A high positive rate occurred more in acute MCA infarction area in the early stage and that reduced by following time.　②The worse vascular stenosis degree was occurred, the widen distribution and the higher grade of HVS were happened.　③HVS appeared in M1 segment trended large part of cerebral infarction, and HVS appeared in the M4~5 segment trended for dispersive cerebral infarction. ④The entire of Willis circle is one of the most important factor of cerebral infarction. The incidence rate of HVS intermitted group was obviously higher than that in integrity group.