目的：评价梯度翻转脂肪抑制技术（LIPO）在3.0T磁共振胰腺弥散加权成像中的应用价值。方法：采用3.0T磁共振对20例正常志愿者分别采用LIPO技术和常规脂肪抑制技术行胰腺DWI扫描（b值800 s/mm2）。由两名经验丰富的影像科医师对所得DWI图像质量情况进行主观评分，并对胰腺表观扩散系数（ADC）值和信噪比（SNR）进行定量测量，应用SPSS 19.0统计学软件，采用单因素方差分析和LSD检验比较LIPO和压脂DWI序列图像中胰腺的ADC值、SNR及图像质量评分值。结果：正常胰腺在DWI LIPO和常规DWI序列中的ADC值无明显统计学差异（P=0.211）；两者的SNR有明显统计学差异（P=0.000 2），且胰腺在DWI LIPO序列上的SNR明显高于常规DWI序列。与常规DWI序列比较，正常胰腺在DWI LIPO序列中伪影及图像模糊程度评分值均具有统计学差异（P值分别为0.001、0.009）。结论：LIPO技术可以在3.0T磁共振胰腺弥散加权成像扫描中提高图像质量。

Objective: To evaluate the clinical value of gradient reversal fat suppression technology(LIPO) in diffusion-weighted MR imaging of normal pancreas at 3.0T. Methods: DWI-LIPO and conventional DWI sequence(b values 800 s/mm2) were performed among twenty volunteers on a 3.0T whole-body MRI system. The ADC value and image quality, including SNR, blurring and artifact level, was evaluated by two experienced radiologists. One-way analysis and LSD test were used to compare DWI-LIPO sequence with conventional DWI sequence through the software SPSS 19.0. Results: There was no statistical difference between two different DWI sequences(P=0.211) in ADC value of normal pancreas. Normal pancreas in DWI with LIPO has more higher SNR than conventional DWI(P=0.000 2). Compared with conventional DWI sequence, there was significantly statistical difference between the artifacts and image blurring degree scores in DWI with LIPO(P=0.001, 0.009). Conclusion: LIPO technology improves the image quality of pancreas DWI at 3.0T MR.