目的：探讨胎儿消化系统异常产前超声特征与妊娠结局。方法：对2012年8月—2014年8月来我院就诊的20～39周的6 328例孕妇进行产科常规检查，并对24例胎儿消化系统异常患者进行追踪观察，结合尸检或出生后手术对照比较。结果：胎儿消化系统异常发生率为0.38%（24/6 328），24例产前超声诊断消化系统异常的胎儿中自然产19例（79.1%），引产及胎死宫内5例（20.8%），全部病例经引产后尸检或分娩后新生儿超声随访证实，产前超声诊断准确率为91.6%，漏诊2例（2例肛门闭锁漏诊），在胎儿消化系统异常中，十二指肠闭锁或狭窄最多见；单发畸形的胎儿预后较好。结论：彩超能够较客观的动态观察胎儿消化道生理性变化及异常，在诊断胎儿消化系统畸形中具有重要的应用价值，对优生优育及胎儿出生后及时治疗具临床指导意义。
Abstract
Objective: To investigate the prenatal ultrasound characteristics and pregnancy outcomes of abnormal digestive system in fetus． Methods: During August 2012 to August 2014, 6 328 pregnant women were detected with ultrasound examination, and we conducted a follow-up study of 24 cases of abnormal fetal digestive system patients, combining with autopsy or after birth control operation. Results: The rate of abnormality in fetus digestive system was 0.38%(24/6 328). There were 19 cases of spontaneous labor(79.1%) and 5 cases of induced abortion(20.8%) in the 24 cases which were suspected with digestive system anomalies． All the cases have been confirmed by the follow-up ultrasound examination and autopsy. The prenatal diagnostic accuracy of ultrasound was 91.6%(22/24）. Two cases were missed(two cases of anal atresia). Duodenal atresia or stenosis was the most common abnormalities of fetal digestive system. Prognosis of fetus with single malformation is better. Conclusion: Color Doppler ultrasound can supply more objective and dynamic observation of the fetal digestive tract physiological changes and the anomaly, which has important application value in the diagnosis of fetus digestive system malformations.
关键词
消化系统畸形 /
胎儿 /
超声检查 /
产前
Key words
Digestive system abnormalities /
Fetus /
Ultrasonography, prenatal
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