目的：探讨超声造影和超微血管显像对乳腺癌微血流及超微血管的诊断价值。方法：回顾性分析经手术病理证实为乳腺癌31例患者的影像学资料，术前分别行超微血管显像（SMI）和超声造影（CEUS）检查，比较两种微血管显像技术对乳腺癌诊断的准确率、血流信号及穿支血管的显示情况。结果：31例共31个乳腺癌病灶，SMI、CEUS以及SMI联合CEUS检查的诊断准确率分别为80.6%、87.1%、93.5%，两者联合检查与单独SMI或CEUS检查相比，差别均有统计学意义（P＜0.05）。对血流信号的显示，SMI检出血流信号丰富12个，血流信号不丰富19个；CEUS表现为高增强及等增强12个，表现为低增强19个，两者具有较好的一致性。对穿支血管的显示，SMI清晰检出常规彩色多普勒超声不能检出的穿支血管3个。结论：超声造影和超微血管显像在乳腺癌诊断中具有重要的临床应用价值，联合应用超声造影与超微血管显像技术有利于提高乳腺癌的诊断准确率。
Abstract
Objective: To explore the diagnosis value of contrast-enhanced ultrasound(CEUS) and superb micro vascular imaging(SMI) for detecting micro-blood flow and super micro-vessels in breast cancer. Methods: The imaging data of 31 cases with breast cancer proved by operation and pathology were analyzed retrospectively, which were examined by SMI and CEUS before operation, comparing the diagnosis accuracy and detecting the blood flow and perforator vessels. Results: Of all 31 cases, the diagnosis accuracy of SMI, CEUS and combined SMI with CEUS was 80.6%, 87.1% and 93.5% respectively, and compared with single SMI or CEUS, the difference was statistically significant(P＜0.05). For displaying the blood flow signals, SMI showed 12 rich blood flow and 19 poor blood flow. Hyper-enhancement and iso-enhancement were seen in 12 cases and hypo-enhancement in 19 cases, revealing that CEUS results are consistent with SMI. For displaying perforator vessels, SMI detected three perforator vessels which couldn’t be detected with color Doppler ultrasound. Conclusion: SMI and CEUS have important clinical values in the diagnosis of breast cancer, the combination of SMI and CEUS can improve the diagnosis accuracy.
关键词
/
乳腺肿瘤 /
超声检查 /
多普勒 /
彩色
Key words
Breast neoplasms /
Ultrasonography, Doppler, color
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基金
上海市闵行区自然科学研究课题（2014MHZ011）。
