目的:探究彩超联合血清CA125、CA724对卵巢良恶性肿瘤的诊断价值。方法:选取2015年1—10月在本院住院手术的卵巢肿瘤病人106例,检查患者彩色超声情况及血清CA125、CA724水平。结果:23例卵巢恶性肿瘤患者CA125、CA724水平均高于83例良性肿瘤患者(P<0.05)。超声诊断卵巢癌符合率为56.5%,三项指标联合检测恶性组阳性率为78.3%,明显高于良性组的37.3%,P<0.05。彩超联合CA125诊断卵巢癌的灵敏度、特异性、准确性和阳性预测值相对较高,且高于三项指标的联合诊断。结论:彩超联合血清肿瘤标志物可以一定程度上提高卵巢良恶性肿瘤的鉴别诊断率。
Abstract
Objective: To explore the diagnostic value of color ultrasonography with serum CA125, CA724 in the benign and malignant ovarian tumor. Method: One hundred and six patients with ovarian tumors who had operation from January to October 2015 in our hospital were detected with color ultrasound and serum CA125 and CA724 levels. Result: The CA125 and CA724 levels of 23 cases with ovarian malignant tumor were higher than that of the 83 patients with benign tumors(P<0.05). The coincidence rate of ultrasound diagnosis was 56.5%. The positive rate of ovarian cancer with combined detections of all three indicators was 78.3% in malignant group, significantly higher than 37.3% of benign group(P<0.05). The sensitivity, specificity, accuracy and the positive predictive value in the diagnosis of ovarian cancer is relatively higher by the detection of color ultrasound combined with CA125, even higher than the joint diagnosis of the three indicators above. Conclusion: Color ultrasonography detection with serum tumor markers can partly improve the differential diagnosis of ovarian benign and malignant tumors.
关键词
卵巢肿瘤 /
超声检查 /
多普勒 /
彩色
Key words
Ovarian neoplasms /
Ultrasonography, Doppler, color
中图分类号:
 
R737.31
R445.1
R446.1
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基金
海南省卫生及计生委普通医学科研资助项目(14A210244)。