目的：探讨磁共振扩散加权成像（DWI）对高、低级别脑膜瘤的鉴别诊断价值。方法：回顾性分析经病理证实的31例低级别脑膜瘤（WHO Ⅰ级）、25例高级别脑膜瘤（WHO Ⅱ～Ⅲ级）患者的DWI资料，并将其分为低级别组、高级别组，分别测量ADC值，比较两组患者之间ADC值的差异，绘制ROC曲线分析ADC值对高级别脑膜瘤的最佳诊断效能。结果：高、低级别脑膜瘤的ADC值分别为（0.72±0.10）×10-3 mm2/s、（0.93±0.12）×10-3 mm2/s，高级别脑膜瘤的ADC值明显低于低级别脑膜瘤，差异具有统计学意义（t=7.30，P<0.01）；ROC曲线分析显示ADC值用于诊断高级别脑膜瘤的最佳临界点为0.83×10-3 mm2/s，其敏感度为84%，特异度为80.6%，准确度为82.1%。结论：磁共振DWI定量参数ADC值对高、低级别脑膜瘤具有较高的鉴别诊断价值，可为患者治疗方案的选择和预后的评估提供更多的信息。

Objective: To investigate the value of MR diffusion weighted imaging(DWI) in the differential diagnosis of high and low-grade meningioma. Methods: Thirty-one patients with low-grade meningioma(WHO Ⅰ) and 25 patients with high-grade meningioma(WHO Ⅱ~Ⅲ) were enrolled in this study, the DWI data were retrospectively analyzed. The patients were divided into low-grade group and high-grade group, and ADC values were measured separately. The difference in ADC value was compared between two groups. The ROC curve was drawn, and the cutoff value for the high-grade meningioma detection was determined. Results: The ADC value of high and low-grade meningioma was (0.72+0.10)×10-3 mm2/s, (0.93+0.12)×10-3 mm2/s respectively, the ADC value of high-grade meningioma was significantly lower than that of low-grade meningioma, the difference was statistically significant(t=7.30, P<0.01); ROC curve analysis showed that the ADC value for the best critical point of diagnosis for high-grade meningioma was 0.83×10-3 mm2/s. The sensitivity was 84%, specificity was 80.6%, accuracy was 82.1%. Conclusion: MR DWI ADC has high value in the differential diagnosis of high and low-grade meningioma, which can provide more information for treatment and prognostic evaluation