摘要
目的:探讨非特异性乳腺炎的MRI表现及与乳腺癌的鉴别诊断。方法:分析2013年1月—2016年3月病理证实的非特异性乳腺炎29例30个病灶的MRI表现,同时随机抽取相同时段经病理证实的乳腺癌患者20例作为对照组,比较2组间在MRI平扫、DWI、DCE、EER、时间-信号曲线(TIC)、MIP表现的异同。结果:30个炎性病变,13例病变区含有脂肪信号,全部病例于T2WI均见有高信号;28例病变环状强化或伴强化分隔,29例DWI呈高信号,ADC值平均(0.707±0.181)×10-3 mm2/s,其中53.3%的病例<0.700×10-3 mm2/s;73.3%的TIC Ⅰ型;EER:平均123%±50%,>80% 26例,≤80% 4例。MIP:21例血运增加。20例乳腺癌,2例于T2WI呈稍高信号,10例表现为向心性环状强化;DWI均呈高信号,ADC值平均(0.874±0.108)×10-3 mm2/s,2例<0.700×10-3 mm2/s,85%的TIC为Ⅱ~Ⅲ型;EER:平均137%±36%,>80% 19例,≤80% 1例;MIP:16例血运增加。以≤0.700×10-3 mm2/s为炎性病变, ADC值对炎性病变的敏感性88.89%, 特异性56.25%, 准确性68%, 二者之间的差异有统计学意义(χ2=6.74,P<0.01)。TIC以Ⅰ型为良性病变,Ⅱ、Ⅲ型为恶性病变,TIC在二者之间有统计学意义(χ2=16.33,P<0.01);EER及MIP在二者之间没有统计学意义(χ2=0.23(校正),P>0.05;χ2=0.62,P>0.05)。结论:非特异性乳腺炎MRI表现具有一定特征性,MRI平扫结合动态增强扫描形态学及血流动力学参数对乳腺癌的鉴别诊断有重要价值。
Abstract
Objective: To investigate the MRI features of nonspecific mastitis and differential diagnosis between nonspecific mastitis and breast cancer. Methods: The MRI findings of 30 lesions of 29 cases with nonspecific mastitis confirmed by pathology from January 2013 to March 2016 were analyzed, and 20 breast cancer patients confirmed by pathology in the same period were randomly selected as control group, and the difference of MRI, DWI, DCE, EER, TIC and MIP findings between the two groups were compared. Result: In 30 lesions, 13 cases showed fat signal, all lesions showed high signal intensity on T2WI; 28 cases had ring reinforcement and enhanced separation, 29 cases showed high signal intensity on DWI, the mean value of ADC was (0.707±0.181)×10-3 mm2/s, and 53.3% of the cases were less than 0.700×10-3 mm2/s; 73.3% cases TIC was type Ⅰ. The mean value of EER was 123%±50%, 26 cases>80%, 4 cases≤80%. MIP: blood supply in 21 cases were increased. In 20 cases with breast cancer, 2 cases showed slightly high signal intensity on T2WI, 10 cases had centripetal and ring reinforced; all cases showed high signal intensity on DWI, the mean value of ADC was (0.874±0.108)×10-3 mm2/s, 2 cases<0.700×10-3 mm2/s, 85% cases TIC type Ⅱ~Ⅲ. The mean value of EER was 137%±36%, 19 cases>80%, 1 case≤80%; MIP: blood supply in 16 cases were increased, with ≤0.700×10-3 mm2/s for inflammatory lesions. The sensitivity, specificity and accuracy of ADC values respectively were 88.89%, 56.25% and 68% in inflammatory lesions, the differences were statistically significant between the two groups(χ2=6.74, P<0.01). TIC type Ⅰ was benign lesions while type Ⅱ and Ⅲ were malignant lesions. There were significant differences in TIC between the two groups(χ2=16.33, P<0.01). There was no significant difference in EER and MIP between the two groups(χ2=0.23(correction), P>0.05; χ2=0.62, P>0.05). Conclusion: MRI findings of nonspecific mastitis have certain characteristics. MRI plain scan combined with dynamic enhanced scan, morphology and hemodynamic parameters have important value in the differential diagnosis of breast cancer.
关键词
乳腺炎 /
乳腺肿瘤 /
磁共振成像
Key words
Mastitis /
Breast neoplasms /
Magnetic resonance imaging
蒋国元,罗义云,柏拉拉,罗洪建.
非特异性乳腺炎的MRI表现及与乳腺癌的鉴别诊断[J]. 中国临床医学影像杂志. 2017, 28(11): 781-784
JIANG Guo-yuan, LUO Yi-yun, BAI La-la, LUO Hong-jian.
MRI findings and differential diagnosis of the nonspecific mastitis with breast cancer[J]. Journal of China Clinic Medical Imaging. 2017, 28(11): 781-784
中图分类号:
R737.9
R655.8
R445.2
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参考文献
[1]蒋国元,李廷超,邱毅,等. 高场MRI对乳腺X线摄影可疑钙化良、恶性病变的鉴别诊断[J]. 重庆医学,2015,44(27):3818-3822.
[2]中国抗癌协会乳腺癌专业委员会. 中国抗癌协会乳腺癌诊治指南与规范(2015版)[J]. 中国癌症杂志,2015,25(9):692-754.
[3]Kaiser WA. 顾雅佳译. 乳腺磁共振征象图谱[M]. 沈阳:辽宁科学技术出版社,2009:72.
[4]路红,刘佩芳,叶兆祥,等. 扩散加权成像中不同扩散敏感系数对乳腺病变的诊断价值[J]. 临床放射学杂志,2010,29(7):892-896.
[5]Lai PH, Ho JT, Chen WL, et al. Brain abscess and necrotic brain tumor: discrimination with proton MR spectroscopy and diffusion-weighted imaging[J]. Am J Neuroradiol, 2002, 23(8): 1369-1377.
[6]黄学莆,姜宏宁,陆孟莹,等. 肉芽肿性小叶性乳腺炎的MRI表现[J]. 中国中西医结合影像学杂志,2013,11(5):480-482.
[7]许玲辉,彭卫军,顾雅佳. 乳腺导管原位癌的MRI表现[J]. 中华放射学杂志,2011,45(2):159-163.
[8]蒋国元,周志琴,邱毅,等. 乳腺中间性钙化的MRI研究[J]. 实用医学杂志,2016,32(2):248-251.
[9]Choi N, Han BK, Choe YH, et al. Three-phase dynamic breast magnetic resonance imaging with two-way subtraction[J]. Comput Assist Tomogr, 2005, 29(6): 834.
基金
本课题为遵义市科技局、遵义市第一人民医院联合科技研发基金资助项目[基金编号:遵市科合社字(2015)14号]。