目的：评估孕早期胎盘体积和血管指数预测小于胎龄儿（SGA）能力。方法：回顾性对比分析242例11~13周+6在我院就诊且随访至胎儿足月出生的无合并症、胎儿畸形单胎妊娠适于胎龄儿（AGA）与SGA胎盘体积、胎盘体积中位倍数值（MOM）、多普勒血管指数。结果：孕早期SGA组胎盘体积、胎盘体积MOM显著低于AGA组（AGA 74.32±20.28，SGA 51.57±11.65，P=0.008；AGA 1.00±0.05，SGA 0.93±0.04，P=0.004）。两组血管指数，包括血管化指数（VI），血流指数（FI）和血管化血流指数（VFI）均无显著差异（VI： P=0.602，FI：P=0.561，VFI：P=0.490）。结论：孕早期三维超声测量的胎盘体积可以预测SGA，而三维能量多普勒血管指数对SGA预测作用不大。
Abstract
Objective: To evaluate the ability of first-trimester placental volume and vascular indices to predict small-for-gestational-age(SGA) birth weight pregnancies. Methods: Retrospective comparative analysis placental volume, multiples of median(MOM）, Doppler vascular index in 242 single pregnancy at 11~13 weeks+6 without complications, fetal malformations in our hospital between appropriate-for-gestational-age(AGA) and SGA at delivery. Results: The placental volume and MOM in the SGA group were significantly lower than those in the AGA group(AGA 74.32±20.28, SGA 51.57±11.65, P=0.008; AGA 1.00±0.05, SGA 0.93±0.04, P=0.004). There were no significant differences in vascular indices, including vascularization index(VI), blood flow index(FI) and vascularized blood flow index(VFI)(VI: P=0.602, FI: P=0.561, VFI: P=0.490). Conclusions: The placenta volume measured by three-dimensional ultrasonography in 11~13 weeks+6 can predict SGA, while the vascular indices have little effect on SGA.
关键词
新生儿 /
胎盘 /
超声检查 /
多普勒 /
彩色
Key words
Infant, newborn /
Placenta /
Ultrasonography, Doppler, color
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