目的:旨在探讨超声下黑斑息肉综合征中息肉及其继发性改变的声像图特征,提高超声医生对该病的认识。方法:回顾性分析我院2012年2月—2016年4月明确诊断为黑斑息肉综合征的6例患者的临床、超声及术后病理资料。结果:6例患者超声均于小肠内发现息肉,且发现息肉引发的肠套叠3例,符合术中所见。结论:超声检查不仅能评估息肉的性状、观察息肉引起的肠套叠、肠梗阻等继发性改变,而且能评估腹部的整体情况,又因其简便无创、实时动态而成为检查黑斑息肉综合征息肉较为有效的手段,为临床诊治提供可靠的依据。
Abstract
Objective: The aim of this paper was to improve the awareness of sonographers to characteristics of polyps and secondary changes of Peutz-Jeghers syndrome(PJS). Methods: A retrospective analysis was made to the ultrasound, clinical data and postoperative pathologies of 6 cases of PJS in our hospital from February 2012 to April 2016. Results: Six cases of polyps caused by PJS and 3 cases of intussusception caused by polyps were found in the small intestine by ultrasound compared with the findings during the operations. Conclusions: Ultrasound is a more effective means for the diagnosis of polyps caused by PJS, because it can evaluate the polyp characters, observe intussusception and intestinal obstruction caused by polyps, assess the overall situation in the abdomen. Ultrasound provides a reliable basis for clinical diagnosis and treatment for its simple, non-invasive and real-time.
关键词
Peutz-Jeghers综合征 /
超声检查
Key words
Peutz-Jeghers syndrome /
Ultrasonography
{{custom_sec.title}}
{{custom_sec.title}}
{{custom_sec.content}}
参考文献
[1]Utsunomiya J, Gocho H, Miyanaga T, et al. Peutz-Jeghers syndrome: its natural course and management[J]. Johns Hopkins Med J, 1975, 136(2): 71-82.
[2]刘虹,赵阳. B超诊断黑斑息肉病1例报告[J]. 宁夏医学杂志,1996,18(5):300.
[3]王子干. 超声诊断Peutz-Jeghers综合征并发小肠5处套叠1例[J]. 中国超声医学杂志,1999,15(3):237.
[4]薛燕,刘钮狰. 黑斑息肉病超声表现1例[J]. 中华超声影像学杂志,2005,14(4):278.
[5]腾华,魏鑫,李静. 彩色多普勒超声诊断Peutz-Jeghers氏综合征并肠套叠1例[J]. 医学影像学杂志,2006,16(6):556.
[6]王晓,吴争勇. 黑斑息肉综合征并发多发性肠套叠超声表现1例[J]. 临床超声医学杂志,2007,9(3):178.
[7]毛旭燕,宁守斌. Peutz-jeghers综合征发病机制和诊疗进展[J]. 胃肠病学,2014,19(8):492-495.
[8]Kang S, Kim ES, Moon A. Simvastatin and lovastatin inhibit breast cell invasion induced by H-Ras[J]. Oneol Rep, 2009, 21(5): 1317-1322.
[9]Van Lier MG, Mathus-Vliegen EM, Wagner A, et al. High cumulative risk of intussusception in patients with Peutz-Jeghers syndrome: time to update surveillance guidelines?[J]. Am J Gastroenterol, 2011, 106(5): 940-945.
[10]唐琪,周平,陈晓,等. Peutz-Jeghers综合征肠套叠的累积危险度与临床特征[J]. 中华消化杂志,2014,34(2):118-120.
[11]Whitelaw SC, Murday VA, Tomlinson IP, et al. Clinical and molecular features of the hereditary mixed polyposis syndrome[J]. Gastroenterology, 1997, 112(2): 327-334.
[12]Wu TT, Rezai B, Rashid A, et al. Genetic alterations and epithelial dysplasia in juvenile polyposis syndrome and sporadic juvenile polyps[J]. Am J Pathol, 1997, 150(3): 939-947.
[13]康素海,程广河,李改兰,等. 黑斑-胃肠道息肉综合征息肉恶变途径分析[J]. 中华临床医师杂志:电子版,2015,10(9):3498-3502.
[14]戴益琛,宋于刚,肖冰,等. 黑斑息肉综合征临床病理研究52例[J]. 武警医学,2008,19(5):450-452.
基金
国家卫生计生委2013—2014年度国家临床重点专科建设项目(2013226)。