自身免疫性胰腺炎影像学诊断现状及研究进展

王  敏; 石  喻; 郭启勇

中国临床医学影像杂志 ›› 2017, Vol. 28 ›› Issue (7) : 521-523.

综述

王敏，石喻，郭启勇

作者信息 +

The present imaging diagnosis and research progress of autoimmune pancreatitis

WANG Min, SHI Yu, GUO Qi-yong

Author information +

文章历史 +

摘要

自身免疫性胰腺炎（Autoimmune pancreatitis，AIP）是自身免疫机制异常所引发的一种特殊类型的慢性胰腺炎。由于缺乏特异性的临床表现和检测指标，AIP在临床上与慢性胰腺炎、胰腺癌难以鉴别，激素冲击疗法的治疗时期直接影响AIP的预后效果，故早期诊断和合理治疗对患者预后极为重要。近年来，无创性影像检查手段在对自身免疫性疾病诊断方面已取得了一些进展，本文对AIP影像诊断现状及研究进展作一综述。

Abstract

Autoimmune pancreatitis(AIP) is a special type of chronic pancreatitis as a result of abnormal autoimmune mechanism. For lack of specific clinical manifestations and detective indicators, it is difficult to differentiate AIP from chronic pancreatitis and pancreatic cancer. Moreover, the treatment timing and course of hormone therapy directly affect the prognosis of AIP. Therefore, early diagnosis and reasonable treatment is very important. In recent years, noninvasive imaging method in autoimmune diseases diagnosis has been progressing. This article will make a review about the research progress of imaging diagnosis in AIP.

导出引用

王敏，石喻，郭启勇. 自身免疫性胰腺炎影像学诊断现状及研究进展[J]. 中国临床医学影像杂志. 2017, 28(7): 521-523

WANG Min, SHI Yu, GUO Qi-yong. The present imaging diagnosis and research progress of autoimmune pancreatitis[J]. Journal of China Clinic Medical Imaging. 2017, 28(7): 521-523

中图分类号： Ｒ657.51 Ｒ814.42 Ｒ814.43 Ｒ445.1

参考文献

[1]Sánchezcastaón M, Del HG, Lópezhoyos M. Autoimmune pancreatitis: an under diagnosed autoimmune disease with clinical, imaging and serological features[J]. Autoimmun Rev, 2010, 9(4): 237-240.
[2]吴朝阳，阿木提江·马合木提，多鲁坤. 自身免疫性胰腺炎误诊为胰腺癌原因辨析[J]. 临床误诊误治，2013，26（5）：26-28.
[3]Kamisawa T, Takuma K, Anjiki H, et al. Differentiation of autoimmune pancreatitis from pancreatic cancer by diffusion-weighted MRI[J]. Am J Gastroenterol, 2010, 105(8): 1870-1875.
[4]Shimosegawa T, Chari ST, Frulloni L, et al. International consensus diagnostic criteria for autoimmune pancreatitis: guidelines of the International Association of Pancreatology[J]. Pancreas, 2011, 40(3): 352-358.
[5]van Heerde MJ, Buijs J, Rauws EA, et al. A comparative study of diagnostic scoring systems for autoimmune pancreatitis[J]. Pancreas, 2014, 43(4): 559-564.
[6]Sah RP, Chari ST, Pannala R, et al. Differences in clinical profile and relapse rate of type 1 versus type 2 autoimmune pancreatitis[J]. Gastroenterology, 2010, 139(1): 140-148.
[7]Kim E, Voaklander R, Kasmin FE, et al. Autoimmune pancreatitis: a multiorgan disease presenting a conundrum for clinicians in the west[J]. Gastroenterol Hepatol, 2015, 11(9): 606-611.
[8]Sugumar A, Levy MJ, Kamisawa T, et al. Endoscopic retrograde pancreatography criteria to diagnose autoimmune pancreatitis: an international multicentre study[J]. Gut, 2011, 60(5): 666-670.
[9]Iwasaki S, Kamisawa T, Koizumi S, et al. Characteristic findings of endoscopic retrograde cholangiopancreatography in autoimmune pancreatitis[J]. Gut Liver, 2015, 9(1): 113-117.
[10]Xin L, He YX, Zhu XF, et al. Diagnosis and treatment of autoimmune pancreatitis: experience with 100 patients[J]. Hepatobil Pancreat Dis Internation Hbpd Int, 2014, 13(6): 642-648.
[11]Takuma K, Kamisawa T, Tabata T, et al. Utility of pancreatography for diagnosing autoimmune pancreatitis[J]. World J Gastroenterol, 2011, 17(18): 2332-2337.
[12]Kanno A, Masamune A, Fujishima F, et al. Diagnosis of autoimmune pancreatitis by EUS-guided FNA using a 22-gauge needle: a prospective multicenter study[J]. Gastrointest Endosc, 2016, 84(5): 797-804.
[13]Mizuno N, Bhatia V, Hosoda W, et al. Histological diagnosis of autoimmune pancreatitis using EUS-guided trucut biopsy: a comparison study with EUS-FNA[J]. J Gastroenterol, 2009, 44(7): 742-750.
[14]Kanno A, Ishida K, Hamada S, et al. Diagnosis of autoimmune pancreatitis by EUS-FNA by using a 22-gauge needle based on the International Consensus Diagnostic Criteria[J]. Gastrointest Endosc, 2012, 76(3): 594-602.
[15]Imai K, Matsubayashi H, Fukutomi A, et al. Endoscopic ultrasonography-guided fine needle aspiration biopsy using 22-gauge needle in diagnosis of autoimmune pancreatitis[J]. Digest Liver Dis Off J Ital Soc Gastroenterol, 2011, 43(11): 869-874.
[16]苏里亚，高瑛，徐光，等. 超声检查对自身免疫性胰腺炎的诊断价值[J]. 中华医学杂志，2012，92（37）：2649-2651.
[17]Graziani R, Mautone S, Ambrosetti MC, et al. Autoimmune pancreatitis: multidetector-row computed tomography(MDCT) and magnetic resonance(MR) findings in the Italian experience[J]. La Radiol Med, 2014, 119(8): 558-571.
[18]Kim JH, Byun JH, Lee SJ, et al. Differential diagnosis of sclerosing cholangitis with autoimmune pancreatitis and periductal infiltrating cancer in the common bile duct at dynamic CT, endoscopic retrograde cholangiography and MR cholangiography[J]. Eur Radiol, 2012, 22(11): 2502-2513.
[19]Ohno Y, Kumagi T, Yokota T, et al. Early pancreatic volume reduction on CT predicts relapse in patients with type 1 autoimmune pancreatitis treated with steroids[J]. Orphanet J Rare Dis, 2016, 11(1): 103.
[20]刘国红，曹尚超，王伟，等. 自身免疫性胰腺炎MRI表现[J]. 医学影像学杂志，2012，22（12）：2067-2070.
[21]Kamisawa T, Takuma K, Anjiki H, et al. Differentiation of autoimmune pancreatitis from pancreatic cancer by diffusion-weighted MRI[J]. Am J Gastroenterol, 2010, 105(8): 1870-1875.
[22]Klaub M, Maier-Hein K, Tjaden C, et al. IVIM DW-MRI of autoimmune pancreatitis: therapy monitoring and differentiation from pancreatic cancer[J]. Eur Radiol, 2016, 26(7): 1-8.
[23]Kamisawa T, Egawa N, Tsuruta K, et al. Can MRCP replace ERCP for the diagnosis of autoimmune pancreatitis?[J]. Abdom Imaging, 2009, 34(3): 381-384.
[24]Shigekawa M, Yamao K, Sawaki A, et al. Is 18F-fluorodeoxyglucose positron emission tomography meaningful for estimating the efficacy of corticosteroid therapy in patients with autoimmune pancreatitis?[J]. J Hepato-biliary-pancreatic Sci, 2010, 17(3): 269-274.
[25]Yonenaga Y, Kushihata F, Watanabe J, et al. Localized 18F-fluorodeoxyglucose uptake at the pancreatic head during remission phase of autoimmune pancreatitis: a case report[J]. Oncol Let, 2016, 12(3): 1801-1805.
[26]Kamisawa T, Anjiki TH, Egawa N, et al. FDG-PET/CT findings of autoimmune pancreatitis[J]. Hepatogastroenterology, 2010, 57(99-100): 447-450.
[27]Puranik AD, Purandare NC, Shah S, et al. Autoimmune pancreatitis: An incidental detection on FDG PET/CT with response to steroid therapy[J]. Ind J Nucl Med, 2013, 28(1): 30-31.
[28]Santhosh S, Bhattacharya A, Harisankar CN, et al. Role of 18F-FDG PET/CT in the management of a case of autoimmune pancreatitis with extrapancreatic manifestation[J]. Clin Nucl Med, 2013, 38(11): 423-425.