超声剪切波弹性成像技术检测移植肝排斥反应的应用研究

王晓静,王岩青,郭朝锋,薛 洁

中国临床医学影像杂志 ›› 2017, Vol. 28 ›› Issue (7) : 526-528.

中国临床医学影像杂志 ›› 2017, Vol. 28 ›› Issue (7) : 526-528.
短篇论著

超声剪切波弹性成像技术检测移植肝排斥反应的应用研究

  • 王晓静,王岩青,郭朝锋,薛  洁
作者信息 +

Detection of transplanted liver rejection by shear wave elastrography

  • WANG Xiao-jing, WANG Yan-qing, GUO Chao-feng, XUE Jie
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摘要

目的:应用超声剪切波弹性成像技术(SWE)检测肝移植术后移植肝排斥反应患者肝硬度数值变化,探讨其临床应用价值。材料与方法:回顾肝移植术后2月内移植肝穿刺活检证实排斥反应患者19例,无排斥反应患者25例,应用SWE技术测量得到肝组织的杨氏模量,即硬度数据,同时检测其血清丙氨酸转氨酶(ALT)、天冬氨酸转氨酶(AST)、总胆红素(TBil),以30例正常人为对照组,用统计学方法比较3组间杨氏模量、血清总胆红素、转氨酶的差异,并进行相关性分析。结果:正常对照组、移植肝正常组、排斥组之间杨氏模量均值Emean、最大值Emax、总胆红素、转氨酶均依次增加,3组间差别有统计学意义(P均<0.05),单因素分析Emean与总胆红素呈正相关(r=0.544,P<0.05)。结论:SWE技术通过量化移植肝硬度大小,反映肝功能损伤程度,为临床提供客观诊疗依据。

关键词

肝移植 / 移植物排斥 / 超声检查

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王晓静,王岩青,郭朝锋,薛 洁. 超声剪切波弹性成像技术检测移植肝排斥反应的应用研究[J]. 中国临床医学影像杂志. 2017, 28(7): 526-528
WANG Xiao-jing, WANG Yan-qing, GUO Chao-feng, XUE Jie. Detection of transplanted liver rejection by shear wave elastrography[J]. Journal of China Clinic Medical Imaging. 2017, 28(7): 526-528
中图分类号: R657.3    R445.1   

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