目的:探讨3.0T磁共振的液体衰减反转恢复成像序列(FLAIR)的高信号血管征(HVS)与磁敏感加权成像(SWI)对急性缺血性脑卒中(AIS)临床对比研究应用价值。方法:62例AIS(<72 h)均行常规MRI、MRA及SWI检查患者,利用FLAIR与SWI联合应用对AIS的近端HVS与血管磁敏感征(SVS)和远端HVS与病灶周围软脑膜血管的侧支循环血管扩张程度相关性分析。结果:在62例AIS中大脑中动脉(MCA)近端高信号HVS阳性39例,阴性23例,分别占总数62.9%、37.1%;远端HVS阳性51例、阴性11例,分别占总数82.2%、17.8%;SVS阳性53例、阴性9例,分别占总数85.5%、14.5%;病灶周围软脑膜血管与同镜像区扩张49例,无扩张13例,分别占总数79.0%、20.1%;AIS的近端HVS征与SWI的SVS征责任血管相关性分析,对t检验具有统计学意义(?字2=8.255,P=0.004,<0.01)。MCA远端在T2 FLAIR的HVS征与病灶周围有、无软脑膜血管显示程度相关性分析对t检验具有一致性(?字2=0.207,P=0.649>0.05)。结论:MCA的SVS和近端HVS对AIS的责任血管具有明显一致性,且SWI对MCA的血栓检出率明显优于T2 FLAIR,MCA远端的HVS征与病灶周围有、无软脑膜血管具有一致性,同时对危重患者优化检查流程,为临床制定正确的治疗方案和预后判断具有重要临床意义。
Abstract
Objective: To investigate the value of high signal vascular sign(HVS) at fluid attenuated inversion recovery imaging(FLAIR) and susceptibility weighted imaging(SWI) in 3.0T magnetic resonance for acute ischemic stroke(AIS). Methods: Sixty-two patients of AIS(<72 h) were underwent MRI. We studied the correlation between proximal HVS of AIS, susceptibility vessel sign(SVS) and distal HVS, dilation of vessels around pia mater combined with FLAIR and SWI. Results: There are 39 cases(62.9%) with proximal HVS of middle cerebral artery(MCA), 51 cases(82.2%) with distal HVS, 53 cases(85.5%) with SVS and 49 cases(79.0%) with dilation of vessels around pia mater. It has correlation between HVS at FLAIR and SVS at SWI of the offending vessel(χ2=8.255, P=0.004). There was consistency between distal HVS of MCA and vessels of pia mater around lesions(χ2=0.207, P=0.649>0.05). Conclusion: There are consistency between SVS of MCA and approximal HVS of offending vessels, distal HVS of MCA and vessels of pia mater around lesions. The detection rate of MCA thrombus at SWI is higher than FLAIR. It is very important to optimize the exam process, make the correct treatment plan and prognosis.
关键词
脑血管意外 /
大脑中动脉 /
磁共振成像
Key words
Cerebrovascular accident /
Middle cerebral artery /
Magnetic resonance imaging
{{custom_sec.title}}
{{custom_sec.title}}
{{custom_sec.content}}
参考文献
[1]高一鹭,王志文. 脑血管病流行病研究进展[J]. 中华神经科杂志,2015,48(4):337-340.
[2]陈泽谷,罗建光,赖玉洁. FLAIR序列远端高信号血管征对急性脑梗死体积的预测作用[J]. 临床放射学杂志,2012,31(9):1215-1218.
[3]黄显军,朱武生,王启章,等. 磁共振液体反转恢复序列高信号血管征对急性大脑中动脉闭塞患者临床预后的评估[J]. 中华神经科杂志,2012,45(3):174-178.
[4]李婵婵,杨艳梅,尹乐康,等. 大脑中动脉闭塞FLAIR血管高信号征与CTA对比研究[J]. 中国医学影像技术,2015,31(7):971-975.
[5]杜先红,刘范林,杨小君. 液体衰减反转恢复序列远端高信号血管征对急性大脑中动脉供血区脑梗死的诊断及预后评估[J]. 中国医学影像学杂志,2014,22(4):310-316.
[6]刘振生,孙勇,周龙江,等. 液体衰减反转恢复成像序列高信号血管征对急性大脑中动脉闭塞血管再通治疗预后的影响[J]. 中华放射学杂志,2016,50(8):615-619.
[7]Cosnard G, Duprez T, Grandin C, et al. Fast FLAIR sequence for detecting major vascular abnormalities during the hyperacute phase of stroke: a comparison with MR angiography[J]. Neuroradiology, 1999, 41(5): 342-346.
[8]Sanossian N, Saver JL, Alger JR, et al. Angiography reveals that fluid-attenuated inversion recovery vascular hyperintensities are due to slow flow, not thrombus[J]. Am J Neuroradiol, 2009, 30(3): 564-568.
[9]Sakamoto Y, Kimura K, Sakai K. Ml susceptibility vessel sign and hyperdense middle cerebral artery sign in hyperacute stroke patients[J]. Eur Neurol, 2012, 68(1): 93-97.
[10]王拥军. 脑侧支循坏及氧化应激对其影响[J]. 中国卒中杂志,2008,3(3):198-201.
[11]陈新建,许开喜,马先军,等. MSCTA评价后循环缺血的椎-基底动脉重度狭窄或闭塞的侧支循环[J]. 南京医科大学学报,2012,32(8):1154-1157.
[12]张俊成,王秀河,郑建辉,等. 大脑中动双层磁敏感血管征对脑梗死分型的预测价值[J]. 临床放射学杂志,2016,35(2):166-169.
[13]许开喜,马先军,陈新建,等. SWI与3D-PCASL联合应用对急性脑梗死的临床预后研究[J]. 实用放射学杂志,2016,32(12):
[14]许开喜,马先军,陈新建,等. SWI对脑梗死侧枝循坏的诊断及临床意义[J]. 中国中西医结合影像学杂志,2016,14(2):153-159.