目的：分析正常中、晚孕胎儿的二、三尖瓣瓣环位移差（APSED）对胎儿心功能研究的价值。方法：将APSED与孕周及二、三尖瓣口舒张早、晚期峰值流速（E、E’、A、A’），左、右心室的每搏量（LSV、RSV）及射血分数（LVEF、RVEF）进行定量分析。结果：正常胎儿各孕周TAPSE均大于MAPSE，差异具有统计学意义（P＜0.05）。胎儿APSED随孕周增加而增加，与孕周呈显著正相关；APSED与E、A、E’、A’、LSV、RSV均呈正相关；与LVEF、RVEF无明显相关性。结论：APSED评价胎儿心功能与传统心功能评价参数具有良好的相关性，能够定量反映胎儿左、右心室纵向运动的差异，可作为评估胎儿心功能的一项新指标。

Objective: To analyze the value of mitral and tricuspid annular plane systolic excursion difference(APSED) of normal fetuses in the second- and third-trimester in case of the study of fetal heart function. Methods: APSED with the peak velocity of early diastole phase(E, E’) and late diastole phase(A, A’) at mitral and tricuspid valve, the stroke volume(SV) and ejection fraction(EF) of both left and right ventricular were quantitatively analyzed. Results: There was a significant difference between TAPSE and MAPSE in different gestational weeks(P<0.05). The APSED of normal fetuses was growing with the increase of gestational weeks, and showed significant positive correlations with gestational week. There was also a positive correlation between APSED and E, E’, A, A’, LSV, RSV, but there was no significant correlation between APSED and LVEF, RVEF. Conclusions: The use of APSED to evaluate fetal heart function has a good correlation with traditional evaluation parameters, and can reflect the difference of the longitudinal motion of fetal left and right ventricles quantitatively. It can be used as a new index to assess the fetal cardiac function.