Progress of research on preclinical Alzheimer’s disease based on functional MRI
SHENG Can1, LIU Fang1, HAN Ying2
Author information+
1.Department of Neurology, the First Hospital of Tsinghua University, Beijing 100016, China;
2.Department of Neurology, Xuanwu Hospital of Capital Medical University, Beijing 100053, China
Alzheimer’s disease(AD) is considered as a continuously pathophysiological process. Special pathological changes of AD has occurred decades prior to the onset of clinical symptoms. Currently, due to the advanced neuroimaging techniques and biochemical tests, variant AD-related biomarkers are gradually identified, making it possible to diagnose AD in the preclinical stage and further intervene the process of the disease. Functional MRI(fMRI), which is helpful to reveal the early brain functional activities in preclinical AD, is the most common form of functional imaging techniques. This review is about researches involving preclinical AD based on fMRI in recent years.
SHENG Can1, LIU Fang1, HAN Ying2.
Progress of research on preclinical Alzheimer’s disease based on functional MRI[J]. Journal of China Clinic Medical Imaging. 2018, 29(5): 359-362
中图分类号：
Ｒ742
Ｒ445.2
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