摘要
目的:探讨MR弥散加权成像(DWI)ADC值和EDC在软组织肿瘤定性诊断中的价值。材料和方法:研究了23例软组织肿瘤DWI。DWI采用SE-EPI序列,弥散敏感系数b分别取0、300s/mm2,同时在3个方向施加弥散敏感梯度场,获得其ADC值和EDC值。结果:①在b=300s/mm2时,良性肿瘤组的ADC值为(1.64±0.15)×10-3mm2/s,恶性肿瘤的ADC值为(1.86±0.19)×10-3mm2/s,恶性肿瘤组的ADC值大于良性肿瘤的ADC值,良、恶性肿瘤组间的ADC值差异有显著性;②在b=300s/mm2时,良性肿瘤组的EDC值为(136.89±44.60)×10-3,恶性肿瘤的EDC值为(160.02±83.23)×10-3,恶性肿瘤组的EDC值大于良性肿瘤的EDC值,良、恶性肿瘤组间的EDC值差异无显著性。结论:在b=300s/mm2时,恶性软组织肿瘤的ADC值大于良性软组织肿瘤的ADC值,良、恶性肿瘤组间的ADC值差异有显著性;恶性肿瘤组的EDC值大于良性肿瘤的EDC值,良、恶性肿瘤组间的EDC值差异无显著性。
Abstract
Objective: To evaluate the diagnostic value of diffusion-weighted imaging(DWI) apparent diffusion coefficient(ADC) and exponential diffusion coefficient(EDC) in differentiation of benign from malignant soft tissue tumors. Methods: Twenty-three patients with soft tissue tumors were studied by DWI. All DWI were performed with SE-EPI technique, which “b” was 0 and 300s/mm2. DWI was analyzed to obtain ADC and EDC of tumor parenchyma. Results: The average value of ADC was(1.86±0.19)×10-3mm2/s for malignant group and (1.64±0.15)×10-3mm2/s for benign group when “b” was 300s/mm2. The mean ADC in benign and malignant tumors had significant difference. The average value of EDC was (160.02±83.23)×10-3 for malignant group and (136.89±44.60)×10-3 for benign group when “b” was 300s/mm2. The mean EDC in benign and malignant tumors has no significant difference. Conclusion: ①ADC is helpful to distinguish malignant tumors from benign tumors when “b” is 300s/mm2. ②EDC has limited value in distinguishing malignant tumors from benign tumors.
关键词
软组织肿瘤 /
磁共振成像 /
弥散
Key words
soft tissue neoplasms /
diffusion magnetic resonance imaging
贾飞鸽;张丽娜;王绍武.
软组织肿瘤MR弥散加权成像量化研究初探[J]. 中国临床医学影像杂志. 2006, 17(5): 272-274
JIA Fei-ge;ZHANG Li-na;WANG Shao-wu.
Preliminary quantitative research of MR diffusion weighted imaging in soft tissue tumors[J]. Journal of China Clinic Medical Imaging. 2006, 17(5): 272-274
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