摘要
目的:研究甲状腺肿瘤的血管病理学特征,评价彩色血管能量成像(CPA)在鉴别甲状腺良恶性肿瘤的应用价值。方法:对60例甲状腺肿瘤患者术前应用CPA检查,术后对手术标本行CD34因子免疫组化染色,计算微血管密度(MVD),行统计学对比分析。结果:甲状腺癌的MVD(51.37±11.17)明显高于甲状腺腺瘤的MVD(21.32±7.95,P<0.05)。甲状腺癌中CPA III级的MVD(53.21±13.11)明显高于II级(36.11±7.92,P<0.05)。甲状腺癌的RI(0.68±0.13)与甲状腺腺瘤的RI(0.54±0.17)比较有统计学意义(P<0.05)。甲状腺癌与甲状腺腺瘤的RI值与MVD均呈正相关(r分别为0.737、0.831),且有统计学意义(P<0.05)。结论:甲状腺肿瘤的CPA血流丰富程度及其RI值和MVD从不同角度反映了甲状腺肿瘤血管生成的特性,可为临床诊断评估甲状腺肿瘤提供新的理论依据。
Abstract
Objective: To evaluate the value of color power angioimaging(CPA) in thyroid tumors by studying the vascular pathology of the tumors. Methods: Thyroid tumors in sixty cases were examined preoperatively by CPA. Microvessel density(MVD) was calculated in surgical specimens after immunohistochemical staining using anti-factor CD34. Results: MVD in thyroid carcinomas(51.37±11.17) was higher than that in adenomas(21.32±7.95, P<0.05). MVD in CPA III of thyroid carcinomas(53.21±13.11) was higher than that in CPA II(36.11±7.92, P<0.05). The RI values of thyroid carcinomas and adenomas all were related positively to MVD(r=0.737, r=0.831, P<0.05). Conclusion: The degree of CPA, RI levels and MVD may provide important information for diagnosing and evaluating thyroid tumors.
关键词
甲状腺肿瘤 /
超声检查 /
多普勒 /
彩色
Key words
thyroid neoplasms /
ultrasonography /
Doppler /
color
金 蓉;李彦敏;王 众.
甲状腺肿瘤的彩色血管能量成像与病理微血管密度的对比研究[J]. 中国临床医学影像杂志. 2006, 17(6): 315-317
JIN Rong;LI Yan-min;WANG Zhong.
Comparative study of color power angioimaging and microvessel density in thyroid tumors[J]. Journal of China Clinic Medical Imaging. 2006, 17(6): 315-317
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