摘要
目的：研究左心室暂时缺血性扩张对男性中－重度冠心病心肌缺血患者的临床意义。方法：从272例进行99Tcm-MIBI静息－负荷心肌灌注显像的连续检查者中，根据负荷显像总分SSS和显像差异总分SDS划分冠心病心肌缺血的程度。筛选出50例中－重度冠心病并有心肌缺血的男性患者，另选择33例显像正常男性为对照组。记录计算机软件同步处理得出的TID数值。结果：中－重度冠心病心肌缺血组与对照组中TID数值分别为1.13±0.13和1.01±0.10，经统计学研究有显著性差异（t=4.214，P<0.01），ROC曲线下面积为0.759，最佳截点值为1.02，当TID>1.18时有最大阳性似然比（P<0.01，Area=0.5）。结论：研究显示应用MIBI心肌灌注显像处理软件同步计算出的TID数值，可以在进行核素负荷－静息心肌显像的男性患者中帮助判断是否存在中－重度冠心病心肌缺血。
Abstract
Objective: To study the clinical significance of left ventricular transient ischemic dilation(TID) with extensive myocardial ischemic coronary artery disease in men. Methods: Fifty male patients with extensive myocardial ischemic coronary artery disease from 272 outpatients and inpatients, and 33 without myocardial ischemic coronary artery disease were enrolled into this study with the latter as the control group. SPECT scintigraphy imaging of stress/rest myocardial perfusion were completed after iv. injection of 740MBq 99Tcm-MIBI. The degree of coronary artery disease and ischemia were graded with SSS and SDS. TID was calculated with software in-synchronism. Results: TID in male patients with extensive myocardial ischemia and those without ischemia was 1.13±0.13 and 1.01±0.10 respectively(t=4.214, P<0.01). There was a significant difference. Area under the ROC curve was 0.759, the best criterion was 1.02, sensitivity was 78%, specificity was 63.6%. TID>1.18 had maximum LR+(P<0.01, Area=0.5). Conclusion: The results suggest that TID assessed using the stress/rest sestamibi SPECT is a useful index for separating extensive myocardial ischemia from those without ischemia in men.
关键词
冠状动脉疾病 /
放射性核素显像
Key words
Coronary disease /
Radionuclide imaging
郑泓明;方风宁;冯 珏;王亚平.
左心室暂时缺血性扩张对男性冠心病患者的临床意义[J]. 中国临床医学影像杂志. 2009, 20(10): 755-757
ZHENG Hong-ming;FANG Feng-ning;FENG Jue;WANG Ya-ping.
Clinical implications of transient left ventricular ischemic dilation of coronary artery disease in men[J]. Journal of China Clinic Medical Imaging. 2009, 20(10): 755-757
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