摘要
目的：探讨3.0T MR一站式成像一次检查完成肿瘤定性诊断和肝动脉、门静脉和肝静脉成像，为临床诊断和术前评价肝癌可切除性提供帮助。资料与方法：应用GE Signa Excite 3.0T超导磁共振扫描仪，对10例正常者和31例临床疑似肝肿瘤患者行多时相三维动态增强MRI扫描，采用三维快速扰相梯度回波（3D FSPGR）序列、利用阵列空间敏感编码技术（ASSET）、零填空技术（ZIP）进行多期扫描成像（肝动脉期、门静脉期、肝静脉期、延迟期）。将动脉期、门静脉期、肝静脉期和延迟期原始图像在ADW 4.2工作站作最大强度（MIP）重建，重组肝动脉、门静脉和肝静脉。测量病灶信号强度，绘出时间－信号曲线，分析病灶的强化特点。结果：10例正常对照组清晰显示肝总动脉、肝固有动脉、肝左、肝右动脉及分支4级以上，清晰显示门静脉主干及分支4~6级以上。23例肝癌和8例血管瘤患者在多时相三维动态增强扫描后能明确诊断，并清晰显示肝癌患者肝动脉受侵所导致的增粗、变形、不规则及门脉癌栓、静脉增粗、迂曲及侧支血管等。结论：采用3D FSPGR序列进行肝脏多时相三维动态增强扫描，在完成肝肿瘤诊断同时，清晰的显示肝内血管结构，对临床诊断和手术决策有重要作用。
Abstract
Objective: To investigate the value of synchronous application of MR angiography(MRA) and dynamic contrast-enhancement in one station scanning of hepatic tumor with 3.0T MR for clinical diagnosis and surgical decision. Methods: Forty-one cases, including 10 normal volunteers and 31 patients with malignant and benign hepatic lesions, were scanned with multi-phase dynamic contrast-enhanced 3D MR imaging adopting 3D fast spoiled gradient recalled(3D FSPGR) and array spatial sensitivity encoding technique (ASSET) and zero-filling interpolation(ZIP). The image data was reconstructed with maximum intensity projection(MIP) on the ADW 4.2 workstation. The signal intensity of hepatic solid lesions was measured and signal intensity-time curve was derived. Results: Common hepatic artery, proper hepatic artery, right and left hepatic arteries, artery branches of grade 4 and above were clearly showed in 10 volunteers, so it was with the portal vein trunk and branches of grade 4 to 6. The diagnosis of 31 patients, including 23 cases of hepatocellular carcinoma and 8 cases of hemangioma, were made correctly with multi-phase dynamic contrast-enhanced 3D MR imaging. Destruction and deformity of hepatic arteries caused by tumor invasion, cancerous embolus of portal vein, and formation of collateral circulation were demonstrated clearly, too. Conclusion: The diagnosis of hepatic tumor and the display of hepatic vessels can be finished synchronously in multi-phase dynamic contrast-enhanced MR scanning with 3D FSPGR, which is of great value for clinical diagnosis and surgical decision.
关键词
肝肿瘤 /
磁共振血管造影术 /
磁共振成像
Key words
Liver neoplasms /
Magnetic resonance angiography /
Magnetic resonance imaging
顾美芳;陆 蓉;顾红梅;施裕新.
3.0T MR一站式检查：一次完成肝脏肿瘤动态增强和MRA成像[J]. 中国临床医学影像杂志. 2009, 20(3): 160-163
GU Mei-fang;LU Rong;GU Hong-mei;SHI Yu-xin.
Synchronous application of MRA and dynamic contrast-enhancement inone station examination of hepatic tumor with 3.0T MR[J]. Journal of China Clinic Medical Imaging. 2009, 20(3): 160-163
中图分类号：
Ｒ735.7
Ｒ445.2
Ｒ814.43
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