摘要
目的：探讨iDOSE（iDOSE，Philips）技术降低肝脏肿瘤患者增强CT辐射剂量的能力。材料与方法：选择肝脏肿瘤患者200例进行常规及低剂量肝脏增强CT扫描。患者随机分成4组（A、B、C、D组），A组常规剂量扫描，滤波反投影（FBP）重建图像，B、C、D组增强扫描门脉期管电流分别较常规降低30%、50%、70%，iDOSE重建图像。定量计算4组图像噪声及对比噪声比（CNR）。对4组图像的诊断信息（肿瘤锐利度、肿瘤与正常肝脏组织对比度、图像主观噪声、图像总体质量）按1~4分（1分最差，4分最优）予以评分。采用完全随机设计的方差分析及秩和检验（Kruskal Wallis）对结果进行比较。结果：客观评估中，iDOSE重建各组的噪声均低于A组（P<0.01）；CNR均高于A组（P<0.01）。主观评估中，4组图像之间肿瘤与正常肝脏组织对比度、主观噪声无差异（P=0.09，P=0.74）；肿瘤锐利度及图像总体质量评估中B、C组与A组之间无差异，而D组低于A组（P<0.01）。结论：对于肝脏肿瘤患者增强CT检查，iDOSE迭代重建技术可使在管电流较常规剂量降低50%的条件下，仍得到与常规剂量FBP重建相当甚至更好的图像质量。
Abstract
Objective: To assess the ability of iDOSE(iDOSE, Philips) iterative reconstruction technique for low-dose hepatic enhanced CT. Materials and Methods: 200 patients with diagnosis of liver tumors were randomly divided into four groups(A, B, C, D). Patients in group A were scanned with routine-dose CT, reconstructed with filtered back projection(FBP). While patients in group B, C, D were scanned with 30%, 50% and 70% radiation dose reduction CT respectively, reconstructed with iDOSE reconstruction. Quantitative noise and contrast-to-noise(CNR) measurements were performed. Qualitative ranking of sharpness of tumors, contrast between tumors and normal liver tissue, noise, and image quality were graded(scale: 1(worse)-4(best)). Data was analyzed using completely randomized design analysis of variance and Kruskal Wallis test. Results: In the comparison of quantitative noise, the groups with iDOSE reconstruction were lower than group A(P<0.01). CNR of groups with iDOSE reconstruction were higher than group A(P<0.01). There was no significant difference among the four groups for tumor tissue contrast and qualitative noise score(P=0.09, P=0.74). There was no significant difference between group B and A, C and A for tumor sharpness and image quality scores. However, a significant difference in tumor sharpness and image quality scores was observed beween group D and group A(P<0.01). Conclusions: When the radiation dose of hepatic enhanced CT scan was reduced by 50%, images maintaining the diagnostic quality of routine dose CT or even better images could be acquired with iDOSE technique.
关键词
肝肿瘤 /
体层摄影术 /
X线计算机
Key words
Liver neoplasms /
Tomography /
X-ray computed
徐 姝;侯 阳;郭启勇.
肝脏低剂量迭代重建增强CT与常规增强CT图像质量及放射剂量的对比研究[J]. 中国临床医学影像杂志. 2013, 24(5): 334-337
XU Shu;HOU Yang;GUO Qi-yong.
A comparative study of image quality and radiation dosage between iterative reconstruction algorithm oflow-dose scans and filtered back project routine-dose scans in hepatic enhanced CT[J]. Journal of China Clinic Medical Imaging. 2013, 24(5): 334-337
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