目的：探讨乳腺浸润性导管癌3.0T MR动态增强MIP血管评分与肿瘤形态、淋巴结转移以及ER、PR表达间的相关性。方法：对28例乳腺浸润性导管癌（共35个病灶）患者行3.0T MR动态增强扫描，重建得到3D MIP血管图像，并对病灶邻近血管数进行评分，分析其与肿瘤形态学、部分生物学指标间的相关性。结果：非肿块型乳腺癌组血管评分比肿块型乳腺癌组高（P<0.05），发生淋巴结转移的乳腺癌组血管评分比未发生淋巴结转移组低（P<0.05），ER阳性乳腺癌组血管评分比ER阴性乳腺癌组低（P<0.01）。结论：浸润性导管癌血管评分与肿瘤形态和淋巴结转移、ER间有一定相关性，分析其血管生成情况，可预测肿瘤生物学行为和评价放化疗效果。
Abstract
Objective: To discuss the relation between the vascular scores of invasive ductal carcinoma(IDC) on MRI-DCE with mass type, lymph node metastasis and ER, PR expression of breast cancer. Methods: All of 28 cases(35 lesions) with breast cancer underwent 3.0T MRI dynamic contrast-enhanced scan, the vascular images of 3D maximum intensity projection were got and the scores of the adjacent blood vessels were estimated. The correlation of vessels scores with tumor morphology(mass type and no-mass type), lymph node metastasis and ER, PR were analyzed. Result: There were higher vessels scores in no-mass type group than mass type(P<0.05), the lymph node metastasis group was higher than no metastasis(P<0.05), the ER positive group was lower than ER negative(P<0.01). Conclusion: The vascular performances of adjacent breast cancer lesions on MRI-DCE are related to mass type and lymph node metastasis, ER expression. It is useful to predicate the biological characteristics and value curative effect of breast cancer.
关键词
乳腺肿瘤 /
磁共振成像
Key words
Breast neoplasms /
Magnetic resonance imaging
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